ORIGINAL RESEARCH article
Front. Oncol.
Sec. Gynecological Oncology
This article is part of the Research TopicMinimally Invasive Options for Uterine Fibroid ManagementView all 7 articles
Robotic versus traditional laparoendoscopic single-site radical hysterectomy with no-manipulation technique: a retrospective cohort study
Provisionally accepted
- 1Department of Gynecologic Oncology, West China Second University Hospital, Sichuan University, Chengdu, China
- 2Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, China
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Background and Objectives: Controversies and challenges over minimally invasive approach in performing radical hysterectomy for early-stage cervical cancer have been raised. This study aimed to determine whether robotic approach was superior to traditional single-site radical hysterectomy with no-manipulation technique for early-stage cervical cancer. Methods: Patients diagnosed with FIGO 2018 stage IB1, IB2 or IIA1 cervical cancer who underwent robotic or traditional single-site radical hysterectomy and pelvic lymphadenectomy between April 2019 and December 2023 were enrolled to assess the perioperative and survival outcomes. Results: 73 patients were included in the robotic group and 51 cases in the traditional group. The robotic group had significantly shorter operative time (236.5±52.8 vs 390.8±73.5 min, p<0.001), less blood loss (50.0 vs 150.0 mL, p<0.001), and shorter drainage time (3.7±1.2 vs 4.7±1.9 days, p=0.001), with a tendency of less conversions and complications compared to the traditional group. The two groups exhibited comparable 3-year disease-free survival (89.8% vs 95.8%, p=0.399) and overall survival (95.8% vs 96.3%, p=0.752) rates. Conclusion: Robotic and traditional single-site radical hysterectomies with no-manipulation techniques are both feasible and safe for early-stage cervical cancer with comparable survival outcomes, though longer follow-up is needed to confirm non-inferiority. The robotic system could significantly reduce surgical difficulties and improve perioperative outcomes.
Keywords: cervical cancer, Laparoendoscopic single-site surgery, No-manipulation technique, Radical hysterectomy, robotic single-site surgery
Received: 07 Jun 2025; Accepted: 27 Jan 2026.
Copyright: © 2026 Chen, Deng, Liu, Yang, Wang, Chen, Yang and Zheng. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Ying Zheng
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