Frontiers in Oncology | Cancer Genetics

Original Research

Published on 28 Sep 2021

RNA Sequencing Data for FFPE Tumor Blocks Can Be Used for Robust Estimation of Tumor Mutation Burden in Individual Biosamples

in Cancer Genetics

Maxim Sorokin
Alexander Gorelyshev
Victor Efimov
Evgenia Zotova
Marianna Zolotovskaia
Elizaveta Rabushko
Denis Kuzmin
Alexander Seryakov
Dmitry Kamashev
Xinmin Li

Frontiers in Oncology

doi 10.3389/fonc.2021.732644

7,484 views
15 citations

Original Research

Published on 28 Sep 2021

Chronic Stress-Induced Gene Changes In Vitro and In Vivo: Potential Biomarkers Associated With Depression and Cancer Based on circRNA- and lncRNA-Associated ceRNA Networks

in Cancer Genetics

Ting Zhou
Mingming Li
Zhijun Xiao
Jian Cai
Weiwei Zhao
Jingjing Duan
Zhen Yang
Zhijun Guo
Yitian Chen
Weijia Cai

Frontiers in Oncology

doi 10.3389/fonc.2021.744251

8,577 views
28 citations

Original Research

Published on 28 Sep 2021

Smoking, DNA Methylation, and Breast Cancer: A Mendelian Randomization Study

in Cancer Genetics

Haibo Tang
Desong Yang
Chaofei Han
Ping Mu

Frontiers in Oncology

doi 10.3389/fonc.2021.745918

8,924 views
13 citations

Brief Research Report

Published on 24 Sep 2021

Statistical Process Control Charts for Monitoring Next-Generation Sequencing and Bioinformatics Turnaround in Precision Medicine Initiatives

in Cancer Genetics

Sneha Rajiv Jain
Wilson Sim
Cheng Han Ng
Yip Han Chin
Wen Hui Lim
Nicholas L. Syn
Nur Haidah Bte Ahmad Kamal
Mehek Gupta
Valerie Heong
Xiao Wen Lee

Frontiers in Oncology

doi 10.3389/fonc.2021.736265

4,856 views
5 citations

Original Research

Published on 24 Sep 2021

Targeted Next-Generation Sequencing of Cancer-Related Genes in a Norwegian Patient Cohort With Head and Neck Squamous Cell Carcinoma Reveals Novel Actionable Mutations and Correlations With Pathological Parameters

in Cancer Genetics

Harsh N. Dongre
Hilde Haave
Siren Fromreide
Fredrik A. Erland
Svein Erik Emblem Moe
Sophia Manueldas Dhayalan
Rasmus Kopperud Riis
Dipak Sapkota
Daniela Elena Costea
Hans Jorgen Aarstad

Frontiers in Oncology

doi 10.3389/fonc.2021.734134

7,560 views
17 citations

Original Research

Published on 23 Sep 2021

Histone Deacetylase Inhibitor Trichostatin A Reduces Endothelial Cell Proliferation by Suppressing STAT5A-Related Gene Transcription

in Cancer Genetics

Yize Li
Yongmei Zhao
Hongyan Peng
Jing Zhang
Lun Bo
Lei Wen
Wenchao Liu
Wendong Bai
Hongmei Zhang

Frontiers in Oncology

doi 10.3389/fonc.2021.746266

4,941 views
9 citations

Original Research

Published on 22 Sep 2021

Gene Expression Profiling for Differential Diagnosis of Liver Metastases: A Multicenter, Retrospective Cohort Study

in Cancer Genetics

Qifeng Wang
Fen Li
Qingming Jiang
Yifeng Sun
Qiong Liao
Huimin An
Yunzhu Li
Zhenyu Li
Lifang Fan
Fang Guo

Frontiers in Oncology

doi 10.3389/fonc.2021.725988

5,450 views
10 citations

Original Research

Published on 22 Sep 2021

LncRNA SNHG7 Regulates Mesenchymal Stem Cell Through the Notch1/Jagged1/Hes-1 Signaling Pathway and Influences Folfirinox Resistance in Pancreatic Cancer

in Cancer Genetics

Dongfeng Cheng
Juanjuan Fan
Kai Qin
Yiran Zhou
Jingrui Yang
Yang Ma
Minmin Shi
Jiabin Jin

Frontiers in Oncology

doi 10.3389/fonc.2021.719855

4,252 views
24 citations

Original Research

Published on 22 Sep 2021

High Expression of SLC16A1 as a Biomarker to Predict Poor Prognosis of Urological Cancers

in Cancer Genetics

Ling Zhang
Zheng-Shuai Song
Zhi-Shun Wang
Yong-Lian Guo
Chang-Geng Xu
Hao Shen

Frontiers in Oncology

doi 10.3389/fonc.2021.706883

4,974 views
13 citations

Review

Published on 20 Sep 2021

Dynamic Interactions of Transcription Factors and Enhancer Reprogramming in Cancer Progression

in Cancer Genetics

Emily Zboril
Hannah Yoo
Lizhen Chen
Zhijie Liu

Frontiers in Oncology

doi 10.3389/fonc.2021.753051

7,008 views
15 citations

Original Research

Published on 20 Sep 2021

Downregulated Expression of CLEC9A as Novel Biomarkers for Lung Adenocarcinoma

in Cancer Genetics

Fang Miao
Zhiguo Lou
Shuhua Ji
Dan Wang
Yaolan Sun
Huan Liu
Chenggang Yang

Frontiers in Oncology

doi 10.3389/fonc.2021.682814

6,078 views
6 citations

Original Research

Published on 17 Sep 2021

High Throughput Transcriptome Data Analysis and Computational Verification Reveal Immunotherapy Biomarkers of Compound Kushen Injection for Treating Triple-Negative Breast Cancer

in Cancer Genetics

Xinkui Liu
Yang Wu
Yingying Zhang
Dechao Bu
Chao Wu
Shan Lu
Zhihong Huang
Yurong Song
Yi Zhao
Fengying Guo

Frontiers in Oncology

doi 10.3389/fonc.2021.747300

5,822 views
7 citations

Original Research

Published on 16 Sep 2021

Genomic Instability-Related LncRNA Signature Predicts the Prognosis and Highlights LINC01614 Is a Tumor Microenvironment-Related Oncogenic lncRNA of Papillary Thyroid Carcinoma

in Cancer Genetics

Xubin Dong
Cong Jin
Danxiang Chen
Yizuo Chen
Zhi-qiang Ye
Xiaohua Zhang
Xiaoli Huang
Wei Zhang
Dian-na Gu

Frontiers in Oncology

doi 10.3389/fonc.2021.737867

6,066 views
13 citations

Original Research

Published on 15 Sep 2021

Machine Learning-Based Comparative Analysis of Pan-Cancer and Pan-Normal Tissues Identifies Pan-Cancer Tissue-Enriched circRNAs Related to Cancer Mutations as Potential Exosomal Biomarkers

in Cancer Genetics

Xuezhu Wang
Yucheng Dong
Zilong Wu
Guanqun Wang
Yue Shi
Yongchang Zheng

Frontiers in Oncology

doi 10.3389/fonc.2021.703461

6,012 views
4 citations

Original Research

Published on 15 Sep 2021

DNA Damage Response and Repair Gene Alterations Increase Tumor Mutational Burden and Promote Poor Prognosis of Advanced Lung Cancer

in Cancer Genetics

Jiawei Dai
Minlin Jiang
Kan He
Hao Wang
Peixin Chen
Haoyue Guo
Wencheng Zhao
Hui Lu
Yayi He
Caicun Zhou

Frontiers in Oncology

doi 10.3389/fonc.2021.708294

9,110 views
28 citations

Original Research

Published on 10 Sep 2021

The Key Gene Expression Patterns and Prognostic Factors in Malignant Transformation from Enchondroma to Chondrosarcoma

in Cancer Genetics

Junqing Wu
Yue Huang
Chengxuan Yu
Xia Li
Limengmeng Wang
Jundong Hong
Daochao Lin
Xiaoping Han
Guoji Guo
Tianye Hu

Frontiers in Oncology

doi 10.3389/fonc.2021.693034

4,805 views
6 citations

Original Research

Published on 09 Sep 2021

Identification of Iron Metabolism-Related Genes as Prognostic Indicators for Lower-Grade Glioma

in Cancer Genetics

Shenbin Xu
Zefeng Wang
Juan Ye
Shuhao Mei
Jianmin Zhang

Frontiers in Oncology

doi 10.3389/fonc.2021.729103

14,987 views
36 citations

Original Research

Published on 09 Sep 2021

Comprehensive Molecular Analyses of a Six-Gene Signature for Predicting Late Recurrence of Hepatocellular Carcinoma

in Cancer Genetics

Yuyuan Zhang
Zaoqu Liu
Xin Li
Long Liu
Libo Wang
Xinwei Han
Zhen Li

Frontiers in Oncology

doi 10.3389/fonc.2021.732447

5,351 views
10 citations

Original Research

Published on 09 Sep 2021

Development and Verification of a Prostate Cancer Prognostic Signature Based on an Immunogenomic Landscape Analysis

in Cancer Genetics

Hong Cheng
Yi Wang
Chunhui Liu
Tiange Wu
Shuqiu Chen
Ming Chen

Frontiers in Oncology

doi 10.3389/fonc.2021.711258

3,663 views
4 citations

Original Research

Published on 08 Sep 2021

Apigenin Inhibits the Histamine-Induced Proliferation of Ovarian Cancer Cells by Downregulating ERα/ERβ Expression

in Cancer Genetics

Manman Liu
Yani Zhang
Qiqi Xu
Guirong Liu
Na Sun
Huilian Che
Tao He

Frontiers in Oncology

doi 10.3389/fonc.2021.682917

7,071 views
29 citations

Original Research

Published on 08 Sep 2021

Tumor Mutation Burden-Associated LINC00638/miR-4732-3p/ULBP1 Axis Promotes Immune Escape via PD-L1 in Hepatocellular Carcinoma

in Cancer Genetics

Feng Qi
Xiaojing Du
Zhiying Zhao
Ding Zhang
Mengli Huang
Yuezong Bai
Biwei Yang
Wenxing Qin
Jinglin Xia

Frontiers in Oncology

doi 10.3389/fonc.2021.729340

7,724 views
23 citations

Correction

Published on 08 Sep 2021

Corrigendum: STAM Prolongs Clear Cell Renal Cell Carcinoma Patients’ Survival via Inhibiting Cell Growth and Invasion

in Cancer Genetics

Tuo Deng
Zihao He
Xiaolu Duan
Di Gu
Chao Cai
Wenqi Wu
Yongda Liu
Guohua Zeng

Frontiers in Oncology

doi 10.3389/fonc.2021.726290

2,042 views
2 citations

Original Research

Published on 08 Sep 2021

MYBL2 Gene Polymorphism Is Associated With Acute Lymphoblastic Leukemia Susceptibility in Children

in Cancer Genetics

Haixia Guo
Na Li
Yaping Sun
Cuiling Wu
Huixia Deng
Ling Xu
Xu Yang

Frontiers in Oncology

doi 10.3389/fonc.2021.734588

3,926 views
3 citations

Review

Published on 06 Sep 2021

Biomarkers and Future Perspectives for Hepatocellular Carcinoma Immunotherapy

in Cancer Genetics

Yuqing He
Mengyao Lu
Jing Che
Qian Chu
Peng Zhang
Yuan Chen

Frontiers in Oncology

doi 10.3389/fonc.2021.716844

8,166 views
34 citations

1,234 articles

articles

RNA Sequencing Data for FFPE Tumor Blocks Can Be Used for Robust Estimation of Tumor Mutation Burden in Individual Biosamples

Chronic Stress-Induced Gene Changes In Vitro and In Vivo: Potential Biomarkers Associated With Depression and Cancer Based on circRNA- and lncRNA-Associated ceRNA Networks

Smoking, DNA Methylation, and Breast Cancer: A Mendelian Randomization Study

Statistical Process Control Charts for Monitoring Next-Generation Sequencing and Bioinformatics Turnaround in Precision Medicine Initiatives

Targeted Next-Generation Sequencing of Cancer-Related Genes in a Norwegian Patient Cohort With Head and Neck Squamous Cell Carcinoma Reveals Novel Actionable Mutations and Correlations With Pathological Parameters

Histone Deacetylase Inhibitor Trichostatin A Reduces Endothelial Cell Proliferation by Suppressing STAT5A-Related Gene Transcription

Gene Expression Profiling for Differential Diagnosis of Liver Metastases: A Multicenter, Retrospective Cohort Study

LncRNA SNHG7 Regulates Mesenchymal Stem Cell Through the Notch1/Jagged1/Hes-1 Signaling Pathway and Influences Folfirinox Resistance in Pancreatic Cancer

High Expression of SLC16A1 as a Biomarker to Predict Poor Prognosis of Urological Cancers

Dynamic Interactions of Transcription Factors and Enhancer Reprogramming in Cancer Progression

Downregulated Expression of CLEC9A as Novel Biomarkers for Lung Adenocarcinoma

High Throughput Transcriptome Data Analysis and Computational Verification Reveal Immunotherapy Biomarkers of Compound Kushen Injection for Treating Triple-Negative Breast Cancer

Genomic Instability-Related LncRNA Signature Predicts the Prognosis and Highlights LINC01614 Is a Tumor Microenvironment-Related Oncogenic lncRNA of Papillary Thyroid Carcinoma

Machine Learning-Based Comparative Analysis of Pan-Cancer and Pan-Normal Tissues Identifies Pan-Cancer Tissue-Enriched circRNAs Related to Cancer Mutations as Potential Exosomal Biomarkers

DNA Damage Response and Repair Gene Alterations Increase Tumor Mutational Burden and Promote Poor Prognosis of Advanced Lung Cancer

The Key Gene Expression Patterns and Prognostic Factors in Malignant Transformation from Enchondroma to Chondrosarcoma

Identification of Iron Metabolism-Related Genes as Prognostic Indicators for Lower-Grade Glioma

Comprehensive Molecular Analyses of a Six-Gene Signature for Predicting Late Recurrence of Hepatocellular Carcinoma

Development and Verification of a Prostate Cancer Prognostic Signature Based on an Immunogenomic Landscape Analysis

Apigenin Inhibits the Histamine-Induced Proliferation of Ovarian Cancer Cells by Downregulating ERα/ERβ Expression

Tumor Mutation Burden-Associated LINC00638/miR-4732-3p/ULBP1 Axis Promotes Immune Escape via PD-L1 in Hepatocellular Carcinoma

Corrigendum: STAM Prolongs Clear Cell Renal Cell Carcinoma Patients’ Survival via Inhibiting Cell Growth and Invasion

MYBL2 Gene Polymorphism Is Associated With Acute Lymphoblastic Leukemia Susceptibility in Children

Biomarkers and Future Perspectives for Hepatocellular Carcinoma Immunotherapy