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Front. Pediatr.
Sec. Pediatric Neurology
Volume 12 - 2024 | doi: 10.3389/fped.2024.1370692

The predicative value of early quantitative electroencephalograph in epilepsy after severe traumatic brain injury in children

Provisionally accepted
  • Xiang Yang No.1 People’s Hospital, Xiangyang, China

The final, formatted version of the article will be published soon.

    Objective: To explore whether early quantitative electroencephalograph (EEG) can predict the development of epilepsy in pediatric patients with severe traumatic brain injury (TBI). Methods: A total of 78 children with severe TBI who were admitted to our hospital were divided into post-traumatic epilepsy (PTE) and non-PTE groups according to whether or not they developed PTE. EEGs of frontal, central and parietal lobes were recorded at the time of their admission. The power values of each frequency band, odds ratio and peak envelope power values of each brain region were statistically analyzed. In addition, the patients were followed up for two years, and the occurrence of PTE was documented. Results: During the follow-up period, PTE occurred in 8 patients. Analysis of EEG signals across different brain regions (frontal, central, and parietal lobes) revealed significant differences between the PTE and non-PTE groups. Patients with PTE exhibited significantly higher δ and θ power values (P < 0.01), lower α/θ ratios (P < 0.01), and elevated θ/β, (δ + θ)/(α + β), and peak envelope power (P < 0.01) compared to those in the non-PTE group. Conclusion: In children with severe TBI, the parameter characterization of early quantitative EEG has potential application in predicting PTE.

    Keywords: early quantitative electroencephalograph (EEG), severe traumatic brain injury (TBI) in children, post-traumatic epilepsy (PTE), peak envelope analysis, Epilepsy

    Received: 26 Jan 2024; Accepted: 10 Jun 2024.

    Copyright: © 2024 Bai. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Wei Bai, Xiang Yang No.1 People’s Hospital, Xiangyang, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.