CASE REPORT article

Front. Pediatr.

Sec. Pediatric Surgery

Volume 13 - 2025 | doi: 10.3389/fped.2025.1531744

This article is part of the Research TopicPediatric Wounds And Tissue Engineering/RegenerationView all 3 articles

Heavy Metal Poisoning and Acute Liver Failure Following Use of a Folk Remedy in a Child with a Burn

Provisionally accepted
Bei-bei  NiuBei-bei Niu1,2Jing-Jing  XuJing-Jing Xu1,2Wen-Wen  JiangWen-Wen Jiang1,2Xia  LinXia Lin1,2Ling-dong  ZhuLing-dong Zhu1,2*
  • 1Children's Hospital Affiliated to Shandong University, Ji nan, China
  • 2Jinan Children's Hospital, Jinan, China

The final, formatted version of the article will be published soon.

Introducion: Folk remedies for the treatment of burns are widely used in China, often due to the belief that they can prevent scarring. However, these remedies may contain complex and unregulated ingredients that can worsen wound conditions, increase infection risk, and lead to systemic heavy metal poisoning.Methods: We report the case of a 1-year-and-8-month-old boy with a burn injury who received treatment with a folk remedy. This treatment led to worsening wound edema and hospital admission. The child developed acute liver failure, requiring plasma exchange and surgical debridement. Laboratory analyses of blood, urine, wound samples, and the folk remedy identified high levels of heavy metals, including chromium, nickel, tin, and lead.Results: The toxicological risks associated with the heavy metal content in folk remedies significantly contributed to the patient's condition. Following standardized medical treatment, liver enzyme levels and coagulation function returned to normal, and the child made a full recovery after 37 days.Conclusion: This case highlights the serious health risks associated with the use of folk remedies in burn management, particularly the potential for wound aggravation and systemic heavy metal poisoning. Clinicians should maintain a high index of suspicion for heavy metal toxicity and apply early, targeted interventions. Furthermore, the optimization of treatment experience for heavy metal poisoning is crucial to improving outcomes for children affected by such exposure, and providing valuable insights for future cases.

Keywords: Folk remedy, burn, Heavy metal posioning, Liver Failure, Surgery, plasma exchange (PE)

Received: 07 Jan 2025; Accepted: 28 Apr 2025.

Copyright: © 2025 Niu, Xu, Jiang, Lin and Zhu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Ling-dong Zhu, Children's Hospital Affiliated to Shandong University, Ji nan, China

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