BRIEF RESEARCH REPORT article
Front. Pediatr.
Sec. Pediatric Infectious Diseases
Volume 13 - 2025 | doi: 10.3389/fped.2025.1543309
This article is part of the Research TopicExploring Infection Dynamics and Interventions in Pediatric Atopic DermatitisView all articles
Molluscum contagiosum with Atopic Dermatitis: A Clinical Retrospective Study of 2,278 Children
Provisionally accepted
- Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
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Objective The dissemination of molluscum contagiosum (MC), a prevalent pediatric cutaneous viral infection, is enhanced upon atopic dermatitis (AD) or compromised epidermal barrier function. However, the potential influence of AD on the course of MC remains controversial. This study aimed to evaluate the influence of AD on MC treatment outcomes Methods: In this clinical retrospective study, we enrolled children with MC and divided them into control (patients with MC alone) and observation (patients with both MC and AD) groups. Parameters such as sex, age, treatment sessions, and treatment duration were recorded for all patients. Efficacy endpoints were defined as complete clearance, with no further MC treatment required for half a year. Chi-squared and Z-tests were performed to compare the clinical and demographic parameters between the groups.Results: Among 2,278 patients, 1,931 (84.77%) had MC alone and 347 (15.23%) had concurrent MC and AD. Significantly differences were observed in treatment sessions (P < 0.05) between the two groups. However, sex, age, and treatment duration did not differ significantly between the groups (P > 0.05).AD increased the number of treatment sessions of MC in children but was not closely related to sex, age, or treatment duration.
Keywords: Children, Molluscum Contagiosum, atopic dermatitis, Treatment, Curettage
Received: 11 Dec 2024; Accepted: 18 Jun 2025.
Copyright: © 2025 Li, Gao, Zeng and Fu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Guili Fu, Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
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