ORIGINAL RESEARCH article
Front. Pediatr.
Sec. Pediatric Otolaryngology
Volume 13 - 2025 | doi: 10.3389/fped.2025.1548142
This article is part of the Research TopicNovel targets in pediatrics: advances in diagnostic and therapeutic approachesView all 9 articles
Clinical diagnosis and treatment of pediatric-onset relapsing polychondritis with airway involvement
Provisionally accepted- Department of Otorhinolaryngology Head and Neck Surgery, Shanghai Children’s Hospital, School of medicine, Shanghai Jiao Tong University, Shanghai, China
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Objective: We herein retrospectively analyzed the clinical characteristics and treatment protocols of children with relapsing polychondritis (RP) with airway involvement. Methods: We reviewed the medical records of eight children with pediatric-onset RP with airway involvement who presented to Shanghai Children’s Hospital from June 2021 to June 2024. All children met Damiani’s criteria for the diagnosis of RP. One child underwent “laryngotracheal reconstruction with hyoid graft + T-tube implantation + bioabsorbable corticosteroid-eluting stent implantation,” while five children underwent “balloon dilatation + T-tube implantation + bioabsorbable corticosteroid-eluting stent implantation.” After the initial surgery, follow-up was performed every two months for a total of six months. Three bioabsorbable corticosteroid-eluting stents were placed in the upper left and upper and lower right T-tubes during this time. Results: All eight children were seen in our department for outpatient follow-up: one child was extubated; five children remained in outpatient follow-up; and the remaining two children continued to be treated in the rheumatology and immunology department due to poor control of their primary disease. Conclusion: Tracheotomy can be used to rapidly improve symptoms of dyspnea in children with RP disease progression. In the stable stage of the disease, the minimally invasive surgical method of “balloon dilatation + T-tube implantation + bioabsorbable corticosteroid-eluting stent implantation” was adopted to reduce secondary injury caused by surgical trauma (to the extent possible) and to improve the survival and quality of life of the children
Keywords: Relapsing polychondritis, Laryngeal and tracheal stenosis, Bioabsorbable corticosteroid-eluting stent implantation, Laryngotracheal reconstruction, pediatric
Received: 19 Dec 2024; Accepted: 29 Apr 2025.
Copyright: © 2025 Wang, Xie, Chen and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Jiarui Chen, Department of Otorhinolaryngology Head and Neck Surgery, Shanghai Children’s Hospital, School of medicine, Shanghai Jiao Tong University, Shanghai, China
Xiaoyan Li, Department of Otorhinolaryngology Head and Neck Surgery, Shanghai Children’s Hospital, School of medicine, Shanghai Jiao Tong University, Shanghai, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.