BRIEF RESEARCH REPORT article

Front. Pediatr.

Sec. Neonatology

Volume 13 - 2025 | doi: 10.3389/fped.2025.1585606

Continuous video recording with simultaneous amplitude-integrated EEG monitoring to improve seizure recognition in newborns.

Provisionally accepted
Anup KageAnup Kage1*Yesenia cruz SantanaYesenia cruz Santana1Ivone Lancolma MalcolmIvone Lancolma Malcolm2caroline franciacaroline francia2michael yoongmichael yoong2David WertheimDavid Wertheim3divyen shahdivyen shah2
  • 1Queen Mary University of London, London, United Kingdom
  • 2The Royal London Hospital, London, England, United Kingdom
  • 3Kingston University, Kingston upon Thames, England, United Kingdom

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Introduction: Seizures in newborn infants are considered a neurological emergency requiring prompt treatment to limit exacerbation of brain injury. Digital monitors incorporating limited channel raw EEG and amplitude-integrated EEG (aEEG/EEG) are widely used. Aims of this study were to determine if continuous video recording with simultaneous aEEG/EEG recording enhances seizure recognition. Methods: Newborns at risk of seizures who underwent neuromonitoring with aEEG/EEG were prospectively recruited to an observational study in a tertiary neonatal centre. Video recordings were commenced after obtaining written consent from parents. Results: Simultaneous video recordings with aEEG/EEG were obtained in 15/47 newborns recruited to study. A total of 116 electrographic seizure episodes were diagnosed on aEEG/EEG. Of these, 8 episodes had clinical manifestations of seizures. There were in addition, there were 56 episodes of abnormal movements identified on video but no corresponding electrical seizure activity; two of these abnormal movements were treated with anti-seizure medication. Discussion: Use of simultaneous video and aEEG/EEG recordings in newborns at risk of seizures is feasible. It not only assists confirmation of the presence of seizures but may also help in identifying movements associated with abnormal neurology that are not seizures

Keywords: newborn seizures, aEEG, EEG, video recordings Abbreviations: aEEG: amplitude-Integrated Electroencephalogram ECG: Electrocardiogram EEG: Electroencephalogram MRI: Magnetic Resonance Imaging HIE: Hypoxic Ischaemic Encephalopathy NICU: Neonatal Intensive Care Unit, Abnormal movements

Received: 28 Feb 2025; Accepted: 21 May 2025.

Copyright: © 2025 Kage, Santana, Malcolm, francia, yoong, Wertheim and shah. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Anup Kage, Queen Mary University of London, London, United Kingdom

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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