ORIGINAL RESEARCH article
Front. Pediatr.
Sec. Pediatric Surgery
Volume 13 - 2025 | doi: 10.3389/fped.2025.1595238
This article is part of the Research TopicAdvances and Challenges in Neonatal Surgery: Congenital and Acquired ConditionsView all 8 articles
Risk factors analysis for significant liver fibrosis of prenatally diagnosed choledochal cysts: a retrospective case-control study
Provisionally accepted
- 1Department of Pathology, Fujian Children's Hospital, Fuzhou, China
- 2Department of General Surgery, Fujian Children's Hospital, Fuzhou, China
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The severity of liver fibrosis and optimal surgical timing in infants with prenatally diagnosed choledochal cysts (CDCs) remain contentious. This study aims to identify risk factors for significant liver fibrosis in prenatally diagnosed CDCs and guide optimal surgical timing.This retrospective case-control study reviewed infants with prenatally diagnosed CDCs between January 2016 and January 2024. Liver fibrosis was staged (S0-S4) using the Batts-Ludwig system. Infants were categorized into mild/no fibrosis (
Keywords: Risk factors, Prenatal Diagnosis, Choledochal Cyst, liver fibrosis, gamma-glutamyl transferase
Received: 17 Mar 2025; Accepted: 28 Apr 2025.
Copyright: © 2025 Zhuang, He, Wu, Fang, Lin and Huang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Yu Lin, Department of General Surgery, Fujian Children's Hospital, Fuzhou, China
Yanbing Huang, Department of General Surgery, Fujian Children's Hospital, Fuzhou, China
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