PERSPECTIVE article

Front. Pediatr.

Sec. Children and Health

Volume 13 - 2025 | doi: 10.3389/fped.2025.1599837

The 'gray zone' in pediatric end-of-life care: bioethical and medico-legal reflections

Provisionally accepted
  • 1Institute of Legal Medicine, Department of Law, University of Macerata, Macerata, Italy
  • 2Research Unit of Bioethics and Humanities, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma,, Rome, Italy
  • 3Department of Clinical Affair, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy

The final, formatted version of the article will be published soon.

Palliative care for children with incurable diseases represents one of the most complex challenges in pediatric medicine. It requires a delicate balance between continuing potentially ineffective therapies and ensuring comfort and dignity during the terminal phase. Decisions involve both the family and the medical team, with a particular focus on the "gray zone," where prognostic uncertainty makes it difficult to determine the most ethical course of action. According to the WHO, palliative care aims to improve the quality of life for both the child and their family, addressing not only physical pain but also psychological and social issues. This article explores the bioethical and medico-legal implications surrounding end-of-life care, parental decision-making autonomy, and the need to always prioritize the child's best interests, while respecting their dignity and values.

Keywords: Palliative Care, End-of-life decision, Bioethics, Pediatrics, death

Received: 25 Mar 2025; Accepted: 13 Jun 2025.

Copyright: © 2025 Scendoni and De Micco. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Roberto Scendoni, Institute of Legal Medicine, Department of Law, University of Macerata, Macerata, Italy

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