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CASE REPORT article

Front. Pediatr.

Sec. Pediatric Orthopedics

Volume 13 - 2025 | doi: 10.3389/fped.2025.1603429

A rare case of acute herbicide poisoning induced pediatric acute osteofascial compartment syndrome

Provisionally accepted
Xueping  ShiXueping Shi1Xin  WangXin Wang2*Pei  GuoPei Guo2*
  • 1Chongqing Medical and Pharmaceutical College, Chongqing, China
  • 2The First Affiliated Hospital of Chongqing Medical and Pharmaceutical College, Chongqing, China

The final, formatted version of the article will be published soon.

Acute osteofascial compartment syndrome (AOCS) is rarely seen in patients with acute herbicide poisoning, and no cases have been reported in children. The correct treatment approach is of vital importance. We report a case of a 13-year-old girl who was admitted to our hospital 17 hours after oral ingestion of “diquat” (a herbicide), and developed clinical symptoms of AOCS 21 hours later. The girl was treated with measures such as removing the toxins, using mannitol for dehydration, and elevating the affected limb. The patient’s AOCS progressed relentlessly; on hospital day 4, after failure of conservative management, she underwent decompressive surgical fasciotomy (DSF) of the lower legs. The girl responded well to continuous renal replacement therapy (CRRT) and continuous fascial decompression treatment. On hospital day 25, she underwent debridement and suture surgery on both lower legs. At discharge, the girl's lower legs bilateral suture incisions were healing well, and the affected legs could stand. Two months later, the girl was able to walk independently.

Keywords: pediatric acute osteofascial compartment syndrome, Herbicide poisoning, Diquat, decompressive surgical fasciotomy, acute osteofascial compartment syndrome

Received: 31 Mar 2025; Accepted: 01 Sep 2025.

Copyright: © 2025 Shi, Wang and Guo. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence:
Xin Wang, The First Affiliated Hospital of Chongqing Medical and Pharmaceutical College, Chongqing, China
Pei Guo, The First Affiliated Hospital of Chongqing Medical and Pharmaceutical College, Chongqing, China

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