ORIGINAL RESEARCH article
Front. Pediatr.
Sec. Pediatric Critical Care
The Risk Factors Of Plasma Transfusions During Resuscitation In Pediatric Burn Patients: A Retrospective Study From 2010 To 2021
Provisionally accepted
- the Central Theatre Air Force Hospital of the Chinese People’s Liberation Army, Datong, Shanxi, Datong, China
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Objectives: To analyze the prevalence and risk factors of plasma transfusions during resuscitation after burns in children. Methods: A retrospective study was carried out at the Burn Treatment Center of the Central Theatre Air Force Hospital of the People's Liberation Army in Datong City, China. The study included pediatric patients (between the ages of two months and 14 years) who were admitted for burns between January 2010 and December 2021. Details of plasma transfusions during the burn resuscitation process for each child were recorded. The association between risk factors and plasma transfusions was evaluated using non-conditional logistic regression. Results: Of the children who suffered from burns, 12.89% (n=174/1350) received plasma transfusions during burn resuscitation. The median amount of plasma transfusions administered was 2.5 units (interquartile range, 1.4). Among the pediatric burn patients who received plasma transfusion, 67.24% did not receive any treatments before being admitted to the hospital, while 14.94% were admitted 6 hours or more after the burns occurred. The total body surface area (TBSA) of pediatric burn patients who received plasma transfusion ranged from 10% to 55%, with a median burn area of 20% of the TBSA and a mean burn area of 22% of the TBSA. Non-conditional logistic regression analysis identified TBSA, white blood cell count (WBC), heart rate, and pre-hospital remedies as significant predictors of plasma transfusion. Conclusion: TBSA (total body surface area), WBC (white blood cell count), heart rate, and pre-hospital interventions can serve as reliable predictors for determining the necessity of plasma transfusions during burn resuscitation. Utilizing these factors can assist blood banks and clinicians in preparing and administering targeted plasma treatments, as well as potentially reducing the overall need for plasma transfusions in pediatric burn patients.
Keywords: Plasma transfusion, Pediatric burn, Burn resuscitation, Risk factors, Pre-hospitalremedies
Received: 14 Apr 2025; Accepted: 27 Oct 2025.
Copyright: © 2025 Zhu, Zhang, Wang, Zhang, Chen, Zhang and Gao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Guangfeng Zhang, ghy21598@163.com
Peigang Gao, gpg322322@163.com
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.