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ORIGINAL RESEARCH article

Front. Pediatr.

Sec. General Pediatrics and Pediatric Emergency Care

Efficacy and safety of arterial blood gas analysis via distal radial artery in children

Provisionally accepted
Ling  YangLing Yang1Xiaoting  ZhouXiaoting Zhou1Shiting  ShuShiting Shu1Heng  DingHeng Ding1Wenjie  MaoWenjie Mao1Gaojun  CaiGaojun Cai2Yidong  ZhaoYidong Zhao1Yu  WanYu Wan1Zhiying  HuangZhiying Huang1*
  • 1Changzhou No.2 People's Hospital, Changzhou, China
  • 2Changzhou Wujin People's Hospital, Changning, Jiangsu Province, China

The final, formatted version of the article will be published soon.

Objective: The distal transradial approach is widely accepted in adult cardiovascular interventions and invasive arterial blood pressure monitoring. However, limited evidence exists regarding the efficacy and safety of arterial blood gas analysis (ABGA) via the distal radial artery (DRA) in children. Methods: This retrospective study evaluated the efficacy and safety of arterial puncture via the DRA compared with the conventional radial artery (CRA) for ABGA in children. Results: A total of 240 children were allocated to either the DRA group (n = 140) or the CRA group (n = 100). The success rate (82.1% vs. 92.0%, p = 0.029) and one-needle success rate (75.7% vs. 89.0%, p = 0.009) were significantly lower in the DRA group. Puncture time in the DRA group was significantly longer than that in the CRA group, whereas hemostasis time was shorter in the DRA group. The incidences of incorrect venipuncture (11.4% vs. 1.0%, p = 0.002) and thumb numbness (5.7% vs. 0.0%, p = 0.022) in the DRA group were significantly higher than those in the CRA group. However, the incidence of hematoma (modified EASY Ia type) in the DRA group was significantly lower than that in the CRA group (8.6% vs. 50.0%, p ˂ 0.001). No significant differences were observed in the incidences of hemorrhage or radial artery occlusion between the two groups. Conclusion: DRA puncture for ABGA in children appears to be a safe and practical alternative to CRA. Although first-attempt success is slightly lower and training is required, the reduced risk of hematoma and shorter hemostasis time make it a promising option for clinical use.

Keywords: Arterial blood gas analysis, Distal radial artery, Radial Artery, conventional radial artery, Children

Received: 13 Apr 2025; Accepted: 19 Nov 2025.

Copyright: © 2025 Yang, Zhou, Shu, Ding, Mao, Cai, Zhao, Wan and Huang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Zhiying Huang, hzy982@njmu.edu.cn

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