CASE REPORT article

Front. Pediatr.

Sec. Neonatology

Volume 13 - 2025 | doi: 10.3389/fped.2025.1612488

This article is part of the Research TopicPrenatal Environmental and Genetic Interactions: An Exploration from Fetal Development to Child HealthView all 5 articles

Placental Chorioangiomatosis: A Case Report and Literature Review

Provisionally accepted
Xixi  WuXixi WuLinbo  ChengLinbo ChengShimao  ZhangShimao ZhangYu  LuYu LuTao  WangTao WangMi  SuMi Su*Qinqin  YuanQinqin Yuan*Huisheng  GeHuisheng Ge*
  • Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan Province, China

The final, formatted version of the article will be published soon.

The placenta is a highly specialized temporary organ during pregnancy. As the hinge of material exchange between mother and fetus, it plays a crucial role in maintaining the fetus's intrauterine life and growth period of fetus. Placental lesions or dysfunction can cause pregnancy diseases. Placental chorioangioma is a benign tumor originating from the placental with an incidence rate of 1%, whose etiology has not yet been fully elucidated. Prenatal diagnosis can usually be done by clinical ultrasound. However, placental chorioangiomatosis, as a placental choriovascular disease, is rarely reported or studied at home and abroad. Due to the unclear etiology and pathogenesis, prenatal diagnosis of placental chorioangiomatosis before early recognition of severe maternal and fetal complications during pregnancy is sparse.Therefore, patients cannot be effectively treated, and pregnancy outcomes are often poor. Herein we provide a case at our hospital and conduct a series of literature reviews around this case to further improve the understanding of placental chorioangiomatosis, and promote early recognition and early intervention.

Keywords: Placental chorioangiomatosis, complications, Prenatal Diagnosis, Pathomechanism, ultrasound

Received: 29 Apr 2025; Accepted: 19 Jun 2025.

Copyright: © 2025 Wu, Cheng, Zhang, Lu, Wang, Su, Yuan and Ge. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence:
Mi Su, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan Province, China
Qinqin Yuan, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan Province, China
Huisheng Ge, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan Province, China

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