CASE REPORT article
Front. Pediatr.
Sec. Pediatric Surgery
Volume 13 - 2025 | doi: 10.3389/fped.2025.1613764
An Anterior Mediastinal Cystic Lesion Pathologically Confirmed as a Mediastinal Pancreatic Pseudocyst after Thoracoscopic Resection: A Rare Case Report and Literature Review
Provisionally accepted
- Xingyi City People's Hospital, Xingyi, Guizhou, China
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Background: Mediastinal lesions have diverse etiologies, with thymoma, cystic teratoma, and lymphoma being relatively prevalent. In contrast, a pancreatic pseudocyst within the mediastinum is exceedingly rare and can often be mistaken for a thymic cyst or teratoma.Presentation: A 17-year-old female presented with a cough and sputum production. Chest CT revealed an anterior mediastinal mass, initially raising the suspicion of a thymic cyst. Thoracoscopic exploration and resection revealed a cystic lesion with a thick wall and brownish fluid. Both frozen section and final histopathological analysis confirmed a mediastinal cyst. Immunohistochemical markers (SYN positive, CK7 positive) led to a diagnosis of mediastinal pancreatic pseudocyst. The patient experienced significant recovery post-surgery, with a marked improvement in symptoms. Conclusion: This case highlights the importance of including mediastinal pancreatic 2 pseudocyst in the differential diagnosis of anterior mediastinal cystic lesions. A thorough clinical and radiological assessment, along with surgical pathology and immunohistochemical profiling, is essential for accurate diagnosis and appropriate management.
Keywords: Anterior Mediastinal Cystic Mass, Pancreatic Pseudocyst, Mediastinal Pancreatic Lesion, CT, x-ray
Received: 18 Apr 2025; Accepted: 16 Jun 2025.
Copyright: © 2025 Zhai, Miao, Xue, Yuan, Jia, Chen and Cha. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Kui Zhai, Xingyi City People's Hospital, Xingyi, Guizhou, China
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