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CASE REPORT article

Front. Pediatr.

Sec. Pediatric Endocrinology

Volume 13 - 2025 | doi: 10.3389/fped.2025.1614566

Pediatric Acute Suppurative Thyroiditis Caused by Eikenella corrodens: A Rare Presentation Revealing Pyriform Sinus Fistula

Provisionally accepted
Fan  CuiFan Cui1,2Lin  ZhaoLin Zhao2Fanchao  DongFanchao Dong3Zhiqiang  YangZhiqiang Yang3Jianjun  DongJianjun Dong1*
  • 1Qilu Hospital, Shandong University, Jinan, China
  • 2Linyi Traditional Chinese Medicine Hospital, Linyi, China
  • 3Linyi Cancer Hospital, Linyi, Shandong Province, China

The final, formatted version of the article will be published soon.

Acute suppurative thyroiditis (AST) is a rare, potentially life-threatening bacterial infection of the thyroid gland, characterized by rapid progression. We report a rare pediatric case of AST caused by Eikenella corrodens, secondary to a pyriform sinus fistula (PSF), initially misdiagnosed as subacute thyroiditis (SAT). A retrospective analysis highlights the diagnostic challenges and emphasizes the need for early suspicion of PSF in recurrent AST. Timely imaging (CT/laryngoscopy) and pathogendirected antibiotics are critical to prevent life-threatening complications. This case underscores the importance of considering atypical pathogens and underlying anatomical anomalies in pediatric AST to guide targeted therapy.

Keywords: suppurative thyroiditis, subacute thyroiditis, Eikenella corrodens, Pyriform sinus fistula, pediatric infection, Branchial cleft anomaly

Received: 15 May 2025; Accepted: 28 Jul 2025.

Copyright: © 2025 Cui, Zhao, Dong, Yang and Dong. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Jianjun Dong, Qilu Hospital, Shandong University, Jinan, China

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