ORIGINAL RESEARCH article
Front. Pediatr.
Sec. Pediatric Oncology
Volume 13 - 2025 | doi: 10.3389/fped.2025.1618810
Global Burden and Trends of Childhood Non-Hodgkin Lymphoma from 1990 to 2021
Provisionally accepted
- 1Nanjing Second Hospital, Nanjing (Zhongfu District), Jiangsu Province, China
- 2Nanjing Medical University, Nanjing, China
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Childhood non-Hodgkin lymphoma (NHL) is a significant contributor to pediatric cancer morbidity and mortality worldwide. This study aims to assess the global, regional, and national burden of childhood NHL from 1990 to 2021, using data from the Global Burden of Disease (GBD) 2021 study.Incidence, mortality, and disability-adjusted life years (DALYs) related to childhood NHL were analyzed across 204 countries and 21 geographic regions using standardized methods from the GBD 2021 study. Estimated annual percentage change (EAPC) and average annual percentage change (AAPC) were calculated to evaluate long-term trends. Frontier and inequality analyses were applied to Incidence, mortality, and disability-adjusted life years (DALYs) related to childhood NHL were analyzed across 204 countries and 21 geographic regions.assess the relationship between sociodemographic development and disease burden.
Keywords: Childhood non-Hodgkin lymphoma, Incidence, Mortality, Health Disparities, Disability-adjusted life years (DALYs)
Received: 28 Apr 2025; Accepted: 09 Jun 2025.
Copyright: © 2025 Xie, Xu, Huang and Zheng. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Yi-Shan Zheng, Nanjing Second Hospital, Nanjing (Zhongfu District), 210003, Jiangsu Province, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.