MINI REVIEW article

Front. Pediatr.

Sec. Pediatric Gastroenterology, Hepatology and Nutrition

Volume 13 - 2025 | doi: 10.3389/fped.2025.1639423

Risk factors for the development of necrotizing enterocolitis in neonatal hemolytic disease: a mini review

Provisionally accepted
Haiyue  YuHaiyue YuGuo  WanxuGuo WanxuYuan  WangYuan WangYunfeng  ZhangYunfeng Zhang*
  • The Second Hospital of Jilin University Department of Pediatric, Changchun, China

The final, formatted version of the article will be published soon.

Hemolytic disease of the newborn (HDN) is a common disease of neonates, and necrotizing enterocolitis (NEC) is a serious gastrointestinal disorder and both occur in the neonatal period that can significantly increase the risk of death in children. Cases of NEC associated with HDN are increasing. The purpose of this paper is to collect and present relevant research data to understand the risk factors associated with necrotizing enterocolitis in neonatal hemolytic disease, and to provide reasonable guidance and reference for clinical work.

Keywords: Hemolytic, Newborn, Enterocolitis, Necrotizing, risk factor, intravenous, Immunoglobulins, exchange transfusion hemolytic

Received: 02 Jun 2025; Accepted: 16 Jul 2025.

Copyright: © 2025 Yu, Wanxu, Wang and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Yunfeng Zhang, The Second Hospital of Jilin University Department of Pediatric, Changchun, China

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