CASE REPORT article
Front. Pediatr.
Sec. Pediatric Infectious Diseases
Volume 13 - 2025 | doi: 10.3389/fped.2025.1655298
Legionella-Induced Suppurative Cervical Lymphadenitis in a Child Diagnosed by Metagenomic Next-Generation Sequencing: A Case Report
Provisionally accepted
- Children's Hospital Affiliated to Shandong University, Ji nan, China
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Legionella pneumophila, primarily associated with respiratory infections, rarely causes extrapulmonary disease. Conventional diagnostic methods for Legionella are often limited. Here we report a case of suppurative cervical lymphadenitis caused by L. pneumophila. And we highlight the critical role of mNGS in enabling rapid and accurate pathogen identification, guiding effective targeted therapy for rare and challenging infections.
Keywords: Legionella pneumophila, Suppurative lymphadenitis, Cervical lymphadenopathy, metagenomic next-generation sequencing, extrapulmonary infection
Received: 27 Jun 2025; Accepted: 13 Oct 2025.
Copyright: © 2025 Li, Liao and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Jian Li, hpylijian@hotmail.com
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.