ORIGINAL RESEARCH article
Front. Pediatr.
Sec. Children and Health
Volume 13 - 2025 | doi: 10.3389/fped.2025.1656234
The Global Burden of Childhood Diarrhea and Its Epidemiological Characteristics From 1990 to 2021
Provisionally accepted
- The Affiliated Huaian No.1 People’s Hospital of Nanjing Medical University, Huai'an, China
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Introduction Diarrhea diseases remains a major contributor to global mortality and morbidity in children. This study aims to provide an updated assessment of rates in diarrhoea prevalence, incidence, mortality, and disability-adjusted life-years (DALYs) from 1990 to 2021, specifically focusing on including prevalence investigation alongside other measures. The analysis is stratified by sex, age, and socio-demographic index (SDI) at global, regional, and national levels.Methods Data for this study was obtained from the 2021 Global Burden of Diseases, Injuries, and Risk Factors Study (GBD). Children aged 0 to 14 years with diarrhea were included in the analysis. The analyses were disaggregated by gender, 3 age categories, 21 GBD regions, 204 nations/territories, and 5 SDI quintiles. Incidence, all-cause mortality, cause-specific mortality, disability-adjusted life years (DALYs), and the corresponding estimated annual percent changes (EAPCs) were investigated.
Keywords: Diarrhea diseases, Global burden of disease, Disability-adjusted life years, Incidence, Prevalence
Received: 30 Jun 2025; Accepted: 11 Aug 2025.
Copyright: © 2025 Zhu, Xu, Zhao, Wang and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Hai-Xiao Wang, The Affiliated Huaian No.1 People’s Hospital of Nanjing Medical University, Huai'an, China
Honggang Wang, The Affiliated Huaian No.1 People’s Hospital of Nanjing Medical University, Huai'an, China
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