ORIGINAL RESEARCH article
Front. Pediatr.
Sec. Pediatric Gastroenterology, Hepatology and Nutrition
Volume 13 - 2025 | doi: 10.3389/fped.2025.1658512
A Single-center Experience of Home Parenteral Nutrition for Pediatric Intestinal Failure
Provisionally accepted
- 1Seoul National University Hospital Department of Surgery, Jongno-gu, Republic of Korea
- 2Seoul National University Bundang Hospital, Seongnam-si, Republic of Korea
- 3Seoul National University College of Medicine, Jongno-gu, Republic of Korea
- 4Seoul National University College of Medicine Department of Pediatrics, Jongno-gu, Republic of Korea
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Background Intestinal failure (IF) in pediatric patients often necessitates home parenteral nutrition (HPN) as a life-saving therapy. While global HPN programs are well-established, data specific to South Korea remain scarce. This study aimed to report the experience with pediatric HPN at a single center in Korea. Methods This retrospective study included 40 pediatric patients receiving HPN between 2009 and 2021 at Seoul National University Children's Hospital. The following data of patients were collected: demographics, diagnoses, surgical factors, HPN protocols, complications including catheter-related bloodstream infection (CRBSI), intestinal failure-associated liver disease (IFALD), hospitalization records, and growth outcomes. Results Forty pediatric patients with IF were followed for a median of 53.5 months. Common IF causes included chronic intestinal pseudo-obstruction syndrome (45.0%) and short bowel syndrome (22.5%). Six (15.0%) patients were weaned off HPN. Complications included CRBSI (60.0%, 0.90/1,000 catheter days) and
Keywords: Home parenteral nutrition, intestinal failure, Pediatrics, Catheter-related bloodstream infection, intestinal failure-associated liver disease
Received: 02 Jul 2025; Accepted: 05 Sep 2025.
Copyright: © 2025 Hwang, Ko, Yang, Youn, Moon, Ko and Kim. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Hyunyoung Kim, Seoul National University Hospital Department of Surgery, Jongno-gu, Republic of Korea
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