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ORIGINAL RESEARCH article

Front. Pediatr.

Sec. Pediatric Gastroenterology, Hepatology and Nutrition

Volume 13 - 2025 | doi: 10.3389/fped.2025.1684339

This article is part of the Research TopicPediatric Gastroenterology And Visualizing The Digestive TractView all 5 articles

Endoscopic ultrasound safety and efficacy in pediatric pancreatobiliary and gastrointestinal disorders: Single-Center Retrospective Trial

Provisionally accepted
Zhang  JiayuZhang Jiayu*deng  zhaohuideng zhaohui*
  • Shanghai Children's Medical Center, Shanghai, China

The final, formatted version of the article will be published soon.

Abstract Background: While endoscopic ultrasound (EUS) is well established as a standard diagnostic and therapeutic tool in adults, its use in children remains limited. This study assessed the indications, safety, and clinical impact of diagnostic and therapeutic EUS in children with pancreatobiliary and gastrointestinal disorders. Methods: We retrospectively analyzed pediatric patients with pancreatobiliary and gastrointestinal disorders who underwent EUS at our institution between January 2022 and June 2025. Results: Fifty-three EUS procedures were conducted in children with a median age of 9.6±3.0 years. Indications for EUS included acute recurrent pancreatitis (n=15), suspected chronic pancreatitis (n=12), suspected choledocholithiasis (n=7), obstructive jaundice (n=5), pancreatic mass (n=1), gastric mucosal lesions (n=6), suspected esophageal lymphoma recurrence (n=1), suspected autoimmune hepatitis (n=1) and pancreatic pseudocyst (PPC, n=5). ERCP was performed during the same anesthesia for all children requiring it post-EUS. Five patients underwent cystogastrostomy for symptomatic PPC with 100% technical and clinical success. The efficacy of EUS in guiding definitive therapeutic decisions and invasive interventions was 100%. Notably, no major complications occurred. Conclusion: EUS is safe and effective diagnostic and therapeutic modality in pediatric patients with pancreatobiliary and gastrointestinal disorders.

Keywords: Biliary Tract Diseases, Endoscopic ultrasonography, gastrointestinal disease, Pancreatic Diseases, Pediatrics

Received: 12 Aug 2025; Accepted: 05 Sep 2025.

Copyright: © 2025 Jiayu and zhaohui. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence:
Zhang Jiayu, Shanghai Children's Medical Center, Shanghai, China
deng zhaohui, Shanghai Children's Medical Center, Shanghai, China

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