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REVIEW article

Front. Pediatr.

Sec. Pediatric Surgery

Gastroschisis: diagnosis, prognosis and treatment options

Provisionally accepted
Ruslan  BilalRuslan Bilal1*Dastan  RustemovDastan Rustemov2Zhenis  SakuovZhenis Sakuov2Zhuldyz  KucherbayevaZhuldyz Kucherbayeva2Sherkhan  ShayakhmetovSherkhan Shayakhmetov2
  • 1School of Medicine, Nazarbayev University, Nur-sultan, Kazakhstan
  • 2University Medical Center Corporate Fund, Astana, Kazakhstan

The final, formatted version of the article will be published soon.

Gastroschisis is a rare congenital anomaly characterized by extrusion of abdominal organs through a defect in the anterior abdominal wall, typically to the right of the umbilical cord. Despite advances in prenatal diagnostics and neonatal surgical care, gastroschisis remains associated with significant morbidity and mortality. This review summarizes recent epidemiological data, etiological hypotheses, diagnostic approaches, treatment strategies, and postoperative complications. Both simple and complicated forms are discussed, with emphasis on the impact of viscero-abdominal disproportion and associated anomalies. Recent modifications in surgical tactics, including staged reduction and innovative siloplasty techniques, are evaluated. The review highlights ongoing challenges in optimizing surgical timing, minimizing complications such as adhesive disease and necrotizing enterocolitis, and improving long-term outcomes.

Keywords: Gastroschisis, Neonatal surgery, Congenital abdominal wall defects, prognosis, surgical treatment, complications, siloplasty, Surgery

Received: 02 Oct 2025; Accepted: 28 Oct 2025.

Copyright: © 2025 Bilal, Rustemov, Sakuov, Kucherbayeva and Shayakhmetov. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Ruslan Bilal, ruslan.bilal@nu.edu.kz

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.