In the original article “Anakinra Therapy for Non-cancer Inflammatory Diseases”, we failed to provide citations for publications relevant to the discovery of IL-1Ra. The citations have now been inserted in the Introduction, Historical Background of IL-1 and IL-1Ra and should read:
“As stated in our review (Cavalli and Dinarello, ), in 1981 we described a circulating suppressor factor from humans during experimental endotoxemia as assayed for specific inhibition of IL-1 activity in vitro (Dinarello et al., ). We believe this circulating suppressor factor was the first description of IL-1Ra, and we confirmed our findings in a report published in Lancet in 1991 using a specific radioimmunoassay for IL-1Ra (Granowitz et al., ). However, in 1984, there was documentation from the group of Jean-Michel Dayer describing a specific inhibitor of IL-1 activity isolated from the urine of patients with monoblastic leukemia (Balavoine et al., ). This was an essential contribution to the history of the discovery of the antagonist. In 1985, there was another report from the Dayer laboratory “Collagenase- and PGE2-Stimulating Activity (Interleukin-1-Like) and Inhibitor in Urine from a Patient with Monocytic Leukemia”, as published in Progress in Leukocyte Biology, vol. 2 (New York, NY: Alan R. Liss, 1985 p. 429). These reports were followed by another publication in the Journal of Clinical Investigation (Balavoine et al., ). As stated in our Review, “the IL-1 inhibitor” isolated from the urine was shown to prevent binding of IL-1 to cells (Seckinger et al., ), thus providing for the first time evidence for its mechanism of action. Because of the widespread and beneficial use of anakinra (the recombinant form of the nature IL-1Ra) to treat human diseases, the contributions of Jean-Michel Dayer as well as those of William Arend are paramount.”
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
References
1
BalavoineJ. F.de RochemonteixB.WilliamsonK.SeckingerP.CruchaudA.DayerJ.-M. (1984). Identification of interleukin 1-like activity and inhibitor(s) in urine from a patient with acute monoblastic leukemia. Lymphokine Res.3:23.
2
BalavoineJ. F.de RochemonteixB.WilliamsonK.SeckingerP.CruchaudA.DayerJ.M. (1986). Prostaglandin E2 and collagenase production by fibroblasts and synovial cells is regulated by urine-derived human interleukin 1 and inhibitor(s). J. Clin. Invest.78, 1120–1124. 10.1172/JCI112669
3
CavalliG.DinarelloC. A. (2018). Anakinra therapy for non-cancer inflammatory diseases. Front. Pharmacol. 9:157. 10.3389/fphar.2018.01157
4
DinarelloC. A.RosenwasserL. J.WolffS. M. (1981). Demonstration of a circulating suppressor factor of thymocyte proliferation during endotoxin fever in humans. J. Immunol.127, 2517–2519.
5
GranowitzE. V.SantosA.PoutsiakaD.CannonJ. G.WilmoreD. A.WolffS. M.et al. (1991). Circulating interleukin-1 receptor antagonist levels during experimental endotoxemia in humans. Lancet338, 1423–1424.
6
SeckingerP.LowenthalJ. W.WilliamsonK.DayerJ. M.MacDonaldH. R. (1987). A urine inhibitor of interleukin 1 activity that blocks ligand binding. J. Immunol.139, 1546–1549.
Summary
Keywords
interleukin 1, IL-1β, IL-1α, rheumatology, inflammation
Citation
Cavalli G and Dinarello CA (2019) Corrigendum: Anakinra Therapy for Non-cancer Inflammatory Diseases. Front. Pharmacol. 10:148. doi: 10.3389/fphar.2019.00148
Received
11 January 2019
Accepted
08 February 2019
Published
08 March 2019
Volume
10 - 2019
Edited and reviewed by
Paolo Sfriso, University of Padova, Italy
Updates
Copyright
© 2019 Cavalli and Dinarello.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Giulio Cavalli cavalli.giulio@gmail.comCharles A. Dinarello cdinare333@aol.com
This article was submitted to Inflammation Pharmacology, a section of the journal Frontiers in Pharmacology
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