The journal retracts the 2018 article cited above.
Following publication, concerns were raised regarding the integrity of the images in the published figures. Image duplication concerns were identified in Figures 1C, 2B, 6C, E, and 7E. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers’ policies. As a result, the data and conclusions of the article have been deemed unreliable and the article has been retracted.
This retraction was approved by the Chief Editors of Frontiers in Pharmacology and the Chief Executive Editor of Frontiers. The authors have not responded to correspondence regarding this retraction.
Summary
Keywords
Icariin (ICA), Insulin Resistance, Txnip, Proteasome, Skeletal muscle cells
Citation
Frontiers Editorial Office (2023) Retraction: Icariin ameliorates palmitate-induced insulin resistance through reducing thioredoxin-interacting protein (TXNIP) and suppressing ER stress in C2C12 myotubes. Front. Pharmacol. 14:1299165. doi: 10.3389/fphar.2023.1299165
Received
22 September 2023
Accepted
22 September 2023
Published
06 October 2023
Approved by
Michael Heinrich, University College London, United Kingdom
Volume
14 - 2023
Updates
Copyright
© 2023 Frontiers Editorial Office.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Frontiers Editorial Office, research.integrity@frontiersin.org
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