In the published article, there was an error in the legend for Figure 4 as published. The original description has ambiguity, which may cause readers to misunderstand. The corrected legend appears below.
FIGURE 4 | In PCa tissues and LNCaP cells, GDPD4-2 expression was decreased compared to non-tumorigenic prostate epithelial cells but increased following treatment with the herb pair Astragalus IV and PESV. (A) Volcano plot showed the lncRNA expression. (B) The differential lncRNA expression in RWPE-1 and LNCaP cells, *p < 0.05 vs. RWPE-1 group. (C) The differential lncRNA expression was analyzed by RT-qPCR in LNCaP cells after treatment with Astragaloside IV-PESV. *p < 0.05 vs. control group, #p < 0.05 vs. Astragaloside IV group, &p < 0.05 vs. PESV group.
In the published article, there was an error in the legend for Figure 5 as published. The original description was not consistent with its results. The corrected legend appears below.
FIGURE 5 | Astragaloside IV- PESV regulates PI3K/AKT/mTOR signaling via GDPD4-2. (A) The expression level of GDPD4-2. (B) LC3 and DAPI immunofluorescence staining were performed to detect autophagy. (C) The LC3, Beclin1, and P62 expression were determined by Western blot. (D) The protein expression of the PI3K/AKT/mTOR signaling pathway. (E) Cell activity was determined by the CCK8 assay. *p < 0.05 vs. NC group, #p < 0.05 vs. sh-GDPD4-2 group, &p < 0.05 vs. Astragaloside IV-PESV group.
In the published article, there was an error in Figure 3 as published. The WB blot image of p-PI3K was mistakenly added in place of p-AKT and PI3K. The corrected Figure 3 and its caption appear below.
FIGURE 3
The authors apologize for these errors and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
Statements
Publisher’s note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.
Summary
Keywords
Astragalus–Scorpio, prostate cancer, PI3K/AKT, Astragaloside IV, polypeptide extract from scorpion venom, autophagy
Citation
You X, Wu Y, Li Q, Sheng W, Zhou Q and Fu W (2025) Corrigendum: Astragalus–Scorpion drug pair inhibits the development of prostate cancer by regulating GDPD4-2/PI3K/AKT/mTOR pathway and autophagy. Front. Pharmacol. 16:1417603. doi: 10.3389/fphar.2025.1417603
Received
15 April 2024
Accepted
05 March 2025
Published
20 March 2025
Volume
16 - 2025
Edited and reviewed by
Olivier Feron, Université catholique de Louvain, Belgium
Updates
Copyright
© 2025 You, Wu, Li, Sheng, Zhou and Fu.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Qing Zhou, 310094@hnucm.edu.cn; Wei Fu, 598356001@qq.com
†These authors share first authorship
Disclaimer
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.