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CORRECTION article

Front. Pharmacol., 08 January 2026

Sec. Translational Pharmacology

Volume 16 - 2025 | https://doi.org/10.3389/fphar.2025.1678247

Correction: Rubidium chloride targets Jnk/p38-mediated NF-κB activation to attenuate osteoclastogenesis and facilitate osteoblastogenesis

  • 1State Key Laboratory of Powder Metallurgy, Central South University, Changsha, China
  • 2Department of Orthopedics, The Second Xiangya Hospital, Central South University, Changsha, China

A Correction on
Rubidium chloride targets Jnk/p38-mediated NF-κB activation to attenuate osteoclastogenesis and facilitate osteoblastogenesis

by Ouyang Z, Huang Q, Liu B, Wu H, Liu T and Liu Y (2019). Front. Pharmacol. 10:584. doi: 10.3389/fphar.2019.00584

There was a mistake in Figure 1B as published. Specifically, the image for the control in the BMMs group was incorrectly selected during figure preparation. The affected image has been replaced with the correct representative image from the original experiments.

Figure 1
Chart A displays bar graphs showing cell viability at different RbCl concentrations over time. Image B features microscopic views of BMMs and RAW264.7 cells treated with varying RbCl doses. Chart C includes bar graphs of TRAP-positive cell counts and areas. Image D presents fluorescence and SEM images showing F-ring formations and bone site resorption at different RbCl concentrations. Chart E shows bar graphs of actin ring numbers and bone site resorption areas.

Figure 1. RbCl attenuates osteoclast formation and function without causing cytotoxicity in vitro. (A) Cell viability of osteoclast precursors after RbCl treatment from 24 to 96 h. (B) In vitro osteoclast formation of primary BMMs and RAW264.7 cells after RANKL and RbCl treatment. (C) Quantification of osteoclastogenesis by RbCl. (D) Formation of F-actin ring and bone resorption pits after RANKL and RbCl treatment. (E) Quantification of F-actin ring and bone resorption pits. *p < 0.05 compared with control. Each experiment was repeated biologically in triplicate independently.

The corrected Figure 1B appears below.

These changes do not affect the scientific conclusions of the article in any way.

The original article has been updated.

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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Keywords: rubidium chloride, osteoclast, osteoblast, MAPK, NF-κB, osteoporosis

Citation: Ouyang Z, Huang Q, Liu B, Wu H, Liu T and Liu Y (2026) Correction: Rubidium chloride targets Jnk/p38-mediated NF-κB activation to attenuate osteoclastogenesis and facilitate osteoblastogenesis. Front. Pharmacol. 16:1678247. doi: 10.3389/fphar.2025.1678247

Received: 02 August 2025; Accepted: 19 December 2025;
Published: 08 January 2026.

Edited and reviewed by:

Peter Vee Sin Lee, The University of Melbourne, Australia

Copyright © 2026 Ouyang, Huang, Liu, Wu, Liu and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Tang Liu, bGl1dGFuZzEyMDRAY3N1LmVkdS5jbg==; Yong Liu, eW9ubGl1QGNzdS5lZHUuY24=

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.