Lan Gao
Neil Smith
Ronald KongA Correction on
Endogenous tetrahydrobiopterin in humans: circadian rhythm, sex, race, age, and disease status
by Gao L, Smith N and Kong R (2025). Front. Pharmacol. 16:1701617. doi: 10.3389/fphar.2025.1701617
Emax was erroneously written as Emax*Age.
A correction has been made to the section Results, Endogenous BH4 concentrations in participants with PBD and PKU, Participants with PKU, Paragraph Number 3:
“The Emax and AM50 values were 12.69 ng/mL and 2.70 years, respectively. There was essentially no change in central trend of endogenous BH4 concentration in participants with PKU aged >2 years. This was confirmed with the Pearson correlation analysis for data in the group aged >2 years, which yielded a correlation coefficient (R) of 0.2265 and a p-value of 0.1656 (Supplementary Figure S1).”
The original article has been updated.
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Keywords: 5,6,7,8-tetrahydrobiopterin (BH4), circadian rhythm, sex, race, age, phenylketonuria (PKU), primary tetrahydrobiopterin deficiency (PBD)
Citation: Gao L, Smith N and Kong R (2025) Correction: Endogenous tetrahydrobiopterin in humans: circadian rhythm, sex, race, age, and disease status. Front. Pharmacol. 16:1764401. doi: 10.3389/fphar.2025.1764401
Received: 10 December 2025; Accepted: 12 December 2025;
Published: 19 December 2025.
Edited and reviewed by:
Xin Wang, East China Normal University, ChinaCopyright © 2025 Gao, Smith and Kong. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Lan Gao, bGdhb0BwdGNiaW8uY29t