Your new experience awaits. Try the new design now and help us make it even better

CORRECTION article

Front. Pharmacol., 22 January 2026

Sec. Inflammation Pharmacology

Volume 17 - 2026 | https://doi.org/10.3389/fphar.2026.1782326

This article is part of the Research TopicPharmacological Modulation of Inflammatory Pathways in Sepsis: Targeting the Cytokine Storm and Septic Oxidative StressView all 8 articles

Correction: Omega 3 fatty acid docosahexaenoic acid (DHA) mitigates inflammatory responses in experimental sepsis

This article is a correction to:

  1. Omega 3 fatty acid docosahexaenoic acid (DHA) mitigates inflammatory responses in experimental sepsis

    1. Read original article
Bianca Portugal Tavares de Moraes,,Bianca Portugal Tavares de Moraes1,2,3Isabelle Moraes-de-Souza,Isabelle Moraes-de-Souza3,4Gabrielle Lacerda de Souza Gomes-Reis,Gabrielle Lacerda de Souza Gomes-Reis3,4Marina Ferreira-Costa,Marina Ferreira-Costa3,4Carolina Medina Coeli da Cunha,Carolina Medina Coeli da Cunha3,4Matheus Augusto Patricio De AlmeidaMatheus Augusto Patricio De Almeida3Vanessa EstatoVanessa Estato3Kauê Francisco Corrêa Souza e SouzaKauê Francisco Corrêa Souza e Souza1Francisco da Silva dos SantosFrancisco da Silva dos Santos5Maria Alice dos Santos Mascarenhas BritoMaria Alice dos Santos Mascarenhas Brito5Patrícia Novaes SoaresPatrícia Novaes Soares6Wilza Arantes Ferreira PeresWilza Arantes Ferreira Peres6Roland ImmlerRoland Immler7Matteo NapoliMatteo Napoli7Patrícia Torres BozzaPatrícia Torres Bozza3Hugo Caire de Castro-Faria-NetoHugo Caire de Castro-Faria-Neto3Markus SperandioMarkus Sperandio7Adriana Ribeiro Silva,,Adriana Ribeiro Silva3,4,5Cassiano Felippe Gonalves-de-Albuquerque,,, Cassiano Felippe Gonçalves-de-Albuquerque1,2,3,5*
  • 1Immunopharmacology Laboratory, Federal University of State of Rio de Janeiro, Rio de Janeiro, Brazil
  • 2Post-Graduation Program in Molecular and Celular Biology, Federal University of State of Rio de Janeiro, Rio de Janeiro, Brazil
  • 3Immunopharmacology Laboratory, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil
  • 4Post-Graduation Program in Molecular and Celular Biology, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil
  • 5Post-Graduation Program in Neuroscience, Fluminense Federal University, Rio de Janeiro, Brazil
  • 6Department of Nutrition and Dietetics - Josué de Castro, Nutrition Institute, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
  • 7Institute of Cardiovascular Physiology and Pathophysiology, Biomedical Center, Ludwig-Maximilians-University Munich, Munich, Germany

A Correction on
Omega 3 fatty acid docosahexaenoic acid (DHA) mitigates inflammatory responses in experimental sepsis

by Moraes BPTd, Moraes-de-Souza I, de Souza Gomes-Reis GL, Ferreira-Costa M, da Cunha CMC, de Almeida MAP, Estato V, Corrêa Souza e Souza KF, dos Santos FdS, dos Santos Mascarenhas Brito MA, Soares PN, Ferreira Peres WA, Immler R, Napoli M, Bozza PT, de Castro-Faria-Neto HC, Sperandio M, Silva AR and Gonçalves-de-Albuquerque CF (2025). Front. Pharmacol. 16:1708348. doi: 10.3389/fphar.2025.1708348

There was a mistake in Figure 7 as published. In Figure 7A, the panels are incorrectly labelled. ‘SHAM + SAL’ was incorrectly captured as ‘SHAM + LNCBL’; ‘SHAM + DHA’ was incorrectly captured as ‘SHAM + LNCDHA’; ‘CLP + SAL’ was incorrectly captured as ‘CLP + LNCBL’; and ‘CLP + DHA’ was incorrectly captured as ‘CLP + LNCDHA’. The corrected Figure 7 appears below:

Figure 7
Panel A shows fluorescence microscopy images of tissue labeled with Rhodamin 6G and FITC, comparing SHAM + SAL, SHAM + DHA, CLP + SAL, CLP + DHA groups. Panels B to F display bar graphs comparing rolling leukocytes, adhesion efficiency, adherent leukocytes, microvascular flow, and lactate levels across the same groups, with significant differences indicated with p-values. Panel G presents colored heat maps of microvascular flow for each group, with a scale from 0 to 300.

Figure 7. DHA improved microcirculation and perfusion in septic mice. Intravital microscopy analysis of cerebral microcirculation in animals induced with sepsis by CLP and treated with DHA 200 mg/kg. (A) Representative image of blood vessels under intravital microscopy for each group. (B) Rolling cells fraction per minute per mm2, (C) Adherent cells per mm2, (D) Leukocyte adhesion efficiency to the endothelium, (E) Lactate levels in plasma. (F) Blood flow intensity assessed by laser speckle imaging, expressed in Arbitrary Perfusion, and (G) Representative images of perfusion under laser speckle for each group 24 h after sepsis induction by CLP. *p < 0.05, ****p < 0.001, as determined by one-way ANOVA with Bonferroni multiple comparison test. N = 4-6. Data were calculated from at least 8 postcapillary venules from 4 to 5 mice.

The original article has been updated.

Generative AI statement

The author(s) declared that generative AI was not used in the creation of this manuscript.

Any alternative text (alt text) provided alongside figures in this article has been generated by Frontiers with the support of artificial intelligence and reasonable efforts have been made to ensure accuracy, including review by the authors wherever possible. If you identify any issues, please contact us.

Publisher’s note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Keywords: docosahexaenoic acid, omega 3, microcirculation, neuroinflammation, intravital microscopy, neutrophils, clp

Citation: Moraes BPTd, Moraes-de-Souza I, Gomes-Reis GLdS, Ferreira-Costa M, Cunha CMCd, Patricio De Almeida MA, Estato V, Souza e Souza KFC, Santos FdSd, dos Santos Mascarenhas Brito MA, Soares PN, Peres WAF, Immler R, Napoli M, Bozza PT, Caire de Castro-Faria-Neto H, Sperandio M, Silva AR and Gonçalves-de-Albuquerque CF (2026) Correction: Omega 3 fatty acid docosahexaenoic acid (DHA) mitigates inflammatory responses in experimental sepsis. Front. Pharmacol. 17:1782326. doi: 10.3389/fphar.2026.1782326

Received: 06 January 2026; Accepted: 12 January 2026;
Published: 22 January 2026.

Edited and reviewed by:

Qinghe Meng, Upstate Medical University, United States

Copyright © 2026 Moraes, Moraes-de-Souza, Gomes-Reis, Ferreira-Costa, Cunha, Patricio De Almeida, Estato, Souza e Souza, Santos, dos Santos Mascarenhas Brito, Soares, Peres, Immler, Napoli, Bozza, Caire de Castro-Faria-Neto, Sperandio, Silva and Gonçalves-de-Albuquerque. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Cassiano Felippe Gonçalves-de-Albuquerque, Y2Fzc2lhbm8uYWxidXF1ZXJxdWVAdW5pcmlvLmJy

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.