Frontiers in Pharmacology | Experimental Pharmacology and Drug Discovery

Review

Published on 18 Sep 2024

N-terminal domain of androgen receptor is a major therapeutic barrier and potential pharmacological target for treating castration resistant prostate cancer: a comprehensive review

in Experimental Pharmacology and Drug Discovery

Ye Chen
Tian Lan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1451957

4,340 views
3 citations

Review

Published on 18 Sep 2024

Extracellular vesicles affecting embryo development in vitro: a potential culture medium supplement

in Experimental Pharmacology and Drug Discovery

Yamei Xue
Haixia Zheng
Yuping Xiong
Kun Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1366992

3,671 views
1 citation

Data Report

Published on 18 Sep 2024

WWAD: the most comprehensive small molecule World Wide Approved Drug database of therapeutics

in Experimental Pharmacology and Drug Discovery

Polina Savosina
Dmitry Druzhilovskiy
Dmitry Filimonov
Vladimir Poroikov

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1473279

2,022 views
1 citation

Original Research

Published on 16 Sep 2024

The identification of potent dual-target monopolar spindle 1 (MPS1) and histone deacetylase 8 (HDAC8) inhibitors through pharmacophore modeling, molecular docking, molecular dynamics simulations, and biological evaluation

in Experimental Pharmacology and Drug Discovery

Huilian Hua
Lixia Guan
Bo Pan
Junyi Gao
Yifei Geng
Miao-Miao Niu
Zhiqin Li
Jindong Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1454523

1,403 views

Original Research

Published on 11 Sep 2024

DJ-1 regulates mitochondrial function and promotes retinal ganglion cell survival under high glucose-induced oxidative stress

in Experimental Pharmacology and Drug Discovery

Hanhan Peng
Haoyu Li
Benteng Ma
Xinyue Sun
Baihua Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1455439

2,181 views
1 citation

Original Research

Published on 11 Sep 2024

The energy metabolism-promoting effect of aconite is associated with gut microbiota and bile acid receptor TGR5-UCP1 signaling

in Experimental Pharmacology and Drug Discovery

Dandan Zhang
Hao Cheng
Jing Wu
Yaochuan Zhou
Fei Tang
Juan Liu
Wuwen Feng
Cheng Peng

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1392385

1,602 views
2 citations

Original Research

Published on 11 Sep 2024

Kaempferol activates chloride secretion via the cAMP/PKA signaling pathway and expression of CFTR in T84 cells

in Experimental Pharmacology and Drug Discovery

Janjira Thaweewattanodom
Chatsri Deachapunya
Sutthasinee Poonyachoti

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1401273

1,235 views
1 citation

Original Research

Published on 10 Sep 2024

Mechanisms of action of Sappan lignum for prostate cancer treatment: network pharmacology, molecular docking and experimental validation

in Experimental Pharmacology and Drug Discovery

Wenna Li
Honglin Jiang
Weina Zhang
Qiuyue Sun
Qiaoli Zhang
Jingnan Xu
Jinchang Huang
Yuxiang Wan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1407525

2,348 views
1 citation

Original Research

Published on 10 Sep 2024

Discovery of key biomarkers in tourette syndrome by network pharmacology

in Experimental Pharmacology and Drug Discovery

Jiali Zhao
Xiaohong Bai

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1397203

1,936 views

Systematic Review

Published on 10 Sep 2024

Effects of total flavonoids of Rhizoma Drynariae on biochemical indicators of bone metabolism: a systematic review and meta-analysis

in Experimental Pharmacology and Drug Discovery

Wei Li
Zechen Zhang
Yuyi Li
Zhenyu Wu
Chengjie Wang
Zhen Huang
Baisheng Ye
Xin Jiang
Xiaolong Yang
Xiaolin Shi

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1443235

1,485 views

Review

Published on 05 Sep 2024

Unraveling the nexus of age, epilepsy, and mitochondria: exploring the dynamics of cellular energy and excitability

in Experimental Pharmacology and Drug Discovery

Wen Xie
Sushruta Koppula
Mayur B. Kale
Lashin S. Ali
Nitu L. Wankhede
Mohit D. Umare
Aman B. Upaganlawar
Ahmed Abdeen
Elturabi E. Ebrahim
Mohamed El-Sherbiny

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1469053

5,009 views
6 citations

Original Research

Published on 04 Sep 2024

Mechanistic study of leukopenia treatment by Qijiao shengbai Capsule via the Bcl2/Bax/CASAPSE3 pathway

in Experimental Pharmacology and Drug Discovery

Siyue Jiang
Pengjiao Wang
Xiaodong Sun
Min Zhang
Shuo Zhang
Yu Cao
Yuben Wang
Li Liu
Xiuli Gao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1451553

1,878 views
2 citations

Original Research

Published on 04 Sep 2024

A general prediction model for compound-protein interactions based on deep learning

in Experimental Pharmacology and Drug Discovery

Wei Ji
Shengnan She
Chunxue Qiao
Qiuqi Feng
Mengjie Rui
Ximing Xu
Chunlai Feng

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1465890

2,540 views

Original Research

Published on 04 Sep 2024

The influence of modified Qing E Formula on the differential expression of serum exosomal miRNAs in postmenopausal osteoporosis patients

in Experimental Pharmacology and Drug Discovery

Junjie Lu
Hui Wu
Huan Jin
Ziyi He
Lin Shen
Chen Ma
Xiaojuan Xu
Zixian Wang
Bo Shuai

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1467298

1,567 views
1 citation

Original Research

Published on 04 Sep 2024

Analysis of gut microbiota-derived metabolites regulating pituitary neuroendocrine tumors through network pharmacology

in Experimental Pharmacology and Drug Discovery

Min Cao
Ping Huang
Lun-shan Xu
Yi-hua Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1403864

2,139 views

Review

Published on 02 Sep 2024

Aberrant glycosylation in schizophrenia: insights into pathophysiological mechanisms and therapeutic potentials

in Experimental Pharmacology and Drug Discovery

Yanchen Feng
Lu Sun
Xue Dang
Diyan Liu
Ziyun Liao
Jianping Yao
Yunke Zhang
Ziqi Deng
Jinyao Li
Min Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1457811

2,359 views
1 citation