Frontiers in Pharmacology | Experimental Pharmacology and Drug Discovery

Brief Research Report

Published on 25 Jun 2024

BRCA1 foci test as a predictive biomarker of olaparib response in ovarian cancer patient-derived xenograft models

in Experimental Pharmacology and Drug Discovery

Federica Guffanti
Ilaria Mengoli
Maria Francesca Alvisi
Giulia Dellavedova
Raffaella Giavazzi
Robert Fruscio
Eliana Rulli
Giovanna Damia

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1390116

1,753 views

Perspective

Published on 21 Jun 2024

Possible opportunities and challenges for traditional Chinese medicine research in 2035

in Experimental Pharmacology and Drug Discovery

Nanqu Huang
Wendi Huang
Jingjing Wu
Sheng Long
Yong Luo
Juan Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1426300

7,255 views
11 citations

Original Research

Published on 20 Jun 2024

Integrated analysis of genes shared between type 2 diabetes mellitus and osteoporosis

in Experimental Pharmacology and Drug Discovery

Fangyu Li
Ying Wang
Jie Cao
Qi Chen
Yuanyuan Gao
Rui Li
Li Yuan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1388205

4,543 views
2 citations

Systematic Review

Published on 20 Jun 2024

Repurposing effect of cardiovascular-metabolic drug to increase lifespan: a systematic review of animal studies and current clinical trial progress

in Experimental Pharmacology and Drug Discovery

Agian Jeffilano Barinda
Harri Hardi
Melva Louisa
Nurul Gusti Khatimah
Rheza Meida Marliau
Immanuel Felix
Muhamad Rizqy Fadhillah
Arief Kurniawan Jamal

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1373458

4,043 views
4 citations

Original Research

Published on 19 Jun 2024

Branched-chain amino acids and L-alanine supplementation ameliorate calcium dyshomeostasis in sarcopenia: New insights for nutritional interventions

in Experimental Pharmacology and Drug Discovery

Elena Conte
Paola Mantuano
Brigida Boccanegra
Paola Imbrici
Giorgia Dinoi
Roberta Lenti
Ornella Cappellari
Donato Cappetta
Antonella De Angelis
Liberato Berrino

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1393746

3,370 views
1 citation

Mini Review

Published on 19 Jun 2024

Blended e-learning and certification for medicines development professionals: results of a 7-year collaboration between King’s College, London and the GMDP Academy, New York

in Experimental Pharmacology and Drug Discovery

Honorio Silva
Peter Stonier
Pravin Chopra
Jacob Coots
Domenico Criscuolo
Soneil Guptha
Stuart Jones
Sandor Kerpel-Fronius
Gustavo Kesselring
Xavier Luria

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1417036

2,002 views
1 citation

Original Research

Published on 18 Jun 2024

KLSD: a kinase database focused on ligand similarity and diversity

in Experimental Pharmacology and Drug Discovery

Yuqian Yuan
Xiaozhu Tang
Hongyan Li
Xufeng Lang
Can Li
Yihua Song
Shanliang Sun
Ye Yang
Zuojian Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1400136

1,255 views

Review

Published on 18 Jun 2024

Naringenin as potent anticancer phytocompound in breast carcinoma: from mechanistic approach to nanoformulations based therapeutics

in Experimental Pharmacology and Drug Discovery

Deena Elsori
Pratibha Pandey
Seema Ramniwas
Rahul Kumar
Sorabh Lakhanpal
Safia Obaidur Rab
Samra Siddiqui
Ajay Singh
Mohd Saeed
Fahad Khan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1406619

6,791 views
5 citations

Original Research

Published on 17 Jun 2024

Effect of repeated intraperitoneal injections of different concentrations of oxycodone on immune function in mice

in Experimental Pharmacology and Drug Discovery

Sumeng Chen
Jingjing Liu
Shaoqiang Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1370663

1,412 views
2 citations

Original Research

Published on 17 Jun 2024

Anti-angiogenic and antioxidant effects of axitinib in human retinal endothelial cells: implications in diabetic retinopathy

in Experimental Pharmacology and Drug Discovery

Francesca Lazzara
Federica Conti
Pradip K. Sasmal
Shanavas Alikunju
Settimio Rossi
Filippo Drago
Chiara Bianca Maria Platania
Claudio Bucolo

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1415846

3,111 views
4 citations

Review

Published on 14 Jun 2024

The reprotoxic adverse side effects of neurogenic and neuroprotective drugs: current use of human organoid modeling as a potential alternative to preclinical models

in Experimental Pharmacology and Drug Discovery

Mariam M. Abady
Ji-Seon Jeong
Ha-Jeong Kwon
Abdullah M. Assiri
Jongki Cho
Islam M. Saadeldin

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1412188

5,035 views
3 citations

Correction

Published on 13 Jun 2024

Corrigendum: Nanofat lysate ameliorates pain and cartilage degradation of osteoarthritis through activation of TGF-β-Smad2/3 signaling of chondrocytes

in Experimental Pharmacology and Drug Discovery

Yanzhi Ge
Wenting Xu
Zuxiang Chen
Haiyan Zhang
Wenbo Zhang
Junjie Chen
Jiefeng Huang
Wenxi Du
Peijian Tong
Letian Shan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1401506

1,043 views

Original Research

Published on 13 Jun 2024

Caffeine regulates both osteoclast and osteoblast differentiation via the AKT, NF-κB, and MAPK pathways

in Experimental Pharmacology and Drug Discovery

Yue Miao
Lei Zhao
Shuwen Lei
Chunyan Zhao
Qiuping Wang
Chao Tan
Chunxiu Peng
Jiashun Gong

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1405173

3,062 views
5 citations

Opinion

Published on 12 Jun 2024

Relative efficacy of five SGLT2 inhibitors: a network meta-analysis of 20 cardiovascular and respiratory outcomes

in Experimental Pharmacology and Drug Discovery

LiGang Huang
Rong Hu
HaiTao Zou

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1419729

1,853 views
2 citations

Systematic Review

Published on 11 Jun 2024

In silico approaches for drug repurposing in oncology: a scoping review

in Experimental Pharmacology and Drug Discovery

Bruno Raphael Ribeiro Cavalcante
Raíza Dias Freitas
Leonardo de Oliveira Siquara da Rocha
Roberto de Souza Batista Dos Santos
Bruno Solano de Freitas Souza
Pablo Ivan Pereira Ramos
Gisele Vieira Rocha
Clarissa Araújo Gurgel Rocha

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1400029

4,164 views
2 citations

Original Research

Published on 11 Jun 2024

Evaluation of the synergistic effects of curcumin-resveratrol co-loaded biogenic silica on colorectal cancer cells

in Experimental Pharmacology and Drug Discovery

Adriana Ochoa-Sanchez
Padmavati Sahare
Surajit Pathak
Antara Banerjee
Miriam Estevez
Asim K. Duttaroy
Gabriel Luna-Bárcenas
Sujay Paul

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1341773

3,280 views
6 citations