Frontiers in Pharmacology | Pharmacogenetics and Pharmacogenomics

Original Research

Published on 13 Sep 2024

An exploratory analysis of associations of genetic variation with the efficacy of tocilizumab in severe COVID-19 patients. A pharmacogenetic study based on next-generation sequencing

in Pharmacogenetics and Pharmacogenomics

Alejandro Durán-Sotuela
Jorge Vázquez-García
Sara Relaño-Fernández
Vanesa Balboa-Barreiro
Juan Fernández-Tajes
Francisco J. Blanco
Ignacio Rego-Pérez

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1426826

1,025 views

Original Research

Published on 04 Sep 2024

Association of SLCO1B1 gene variants with angiotensin-converting enzyme inhibitor-induced cough in a Pakistani hypertensive cohort

in Pharmacogenetics and Pharmacogenomics

Arooj Fatima Sheikh
Nayla Munawar
Rukhsana Nawaz
Hizbullah Khan
Mehwish Rafique
Faryal Jahan
Sagheer Ahmed

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1441251

1,253 views

Original Research

Published on 23 Aug 2024

Transcriptome analysis to explore the mechanism of downregulated TNIK influencing the effect of risperidone

in Pharmacogenetics and Pharmacogenomics

Ruixue Yuan
Yaojing Li
Xiangyi Li
Yingmei Fu
Ailing Ning
Dongxiang Wang
Ran Zhang
Shunying Yu
Qingqing Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1431923

1,799 views

Systematic Review

Published on 21 Aug 2024

Genetic polymorphisms and platinum-induced hematological toxicity: a systematic review

in Pharmacogenetics and Pharmacogenomics

Yi Zheng
Mimi Tang
Zheng Deng
Pei Cai

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1445328

2,263 views
1 citation

Review

Published on 20 Aug 2024

Review of pharmacogenetics of antiseizure medications: focusing on genetic variants of mechanistic targets

in Pharmacogenetics and Pharmacogenomics

Chih-Hsiang Lin
Chen-Jui Ho
Shih-Ying Chen
Yan-Ting Lu
Meng-Han Tsai

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1411487

2,402 views

Methods

Published on 14 Aug 2024

CYP2D6 copy number determination using digital PCR

in Pharmacogenetics and Pharmacogenomics

Wendy Y. Wang
Lancy Lin
Erin C. Boone
Junko Stevens
Andrea Gaedigk

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1429286

3,696 views
1 citation

Case Report

Published on 12 Aug 2024

Case report: Drug reaction with eosinophilia and systemic symptoms (DRESS) induced by ceftazidime in a connective tissue disease (CTD) patient

in Pharmacogenetics and Pharmacogenomics

Rui Dai
Ziran Niu
Yang Yang
Xin Liu
Bo Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1403390

1,827 views
1 citation

Case Report

Published on 01 Aug 2024

Toxic epidermal necrolysis caused by phenobarbital: a case report and literature review

in Pharmacogenetics and Pharmacogenomics

Jie Cheng
Hui Li
Yan Li
Xiao Li
Jianjun Wang
Xin Huang
XueYan Cui

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1433506

1,993 views
1 citation

Original Research

Published on 29 Jul 2024

Genetic variability in the glucocorticoid pathway and treatment outcomes in hospitalized patients with COVID-19: a pilot study

in Pharmacogenetics and Pharmacogenomics

Patricija Štampar
Tanja Blagus
Katja Goričar
Petra Bogovič
Gabriele Turel
Franc Strle
Vita Dolžan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1418567

1,395 views
1 citation

Original Research

Published on 26 Jul 2024

Glycerophosphoinositol modulates FGA and NOTCH3 in exercise-induced muscle adaptation and colon cancer progression

in Pharmacogenetics and Pharmacogenomics

Hongbiao Luo
Wei Luo
Ning Ding
Huimin Zhu
Jiahui Lai
Qingzhu Tang
Yongheng He

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1430400

1,730 views
2 citations

Editorial

Published on 24 Jul 2024

Editorial: State of the science of pharmacogenomics implementation in healthcare systems and communities

in Pharmacogenetics and Pharmacogenomics

Sean P. David
Beth Devine
Latha Palaniappan
Elisa J. Houwink

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1463384

1,059 views
2 citations

Original Research

Published on 23 Jul 2024

Pharmacogenetic educational needs and the role of pharmacogenetics in primary care: a focus group study with multiple perspectives

in Pharmacogenetics and Pharmacogenomics

Maaike E. Ferwerda
Jessica A. Wright
Razan M. El Melik
Jesse J. Swen
Elisa J. Houwink

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1404370

1,984 views
1 citation

Review

Published on 22 Jul 2024

Molecular biomarkers of leukemia: convergence-based drug resistance mechanisms in chronic myeloid leukemia and myeloproliferative neoplasms

in Pharmacogenetics and Pharmacogenomics

Meike Kaehler
Nikolas von Bubnoff
Ingolf Cascorbi
Sivahari Prasad Gorantla

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1422565

2,916 views
1 citation

Original Research

Published on 16 Jul 2024

Overexpression of Nrf2 in bone marrow mesenchymal stem cells promotes B-cell acute lymphoblastic leukemia cells invasion and extramedullary organ infiltration through stimulation of the SDF-1/CXCR4 axis

in Pharmacogenetics and Pharmacogenomics

Lin Zheng
Chengyun Pan
Dan Ma
Qin Shang
Tianzhen Hu
Tianzhuo Zhang
Qian Kang
Xiuying Hu
Shuyun Cao
Li Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1393482

3,198 views

Editorial

Published on 16 Jul 2024

Editorial: Is there still room for pharmacogenetics in 2023? The cases of infectious diseases and oncology

in Pharmacogenetics and Pharmacogenomics

Alessandra Manca
Jessica Cusato

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1457733

751 views

Editorial

Published on 07 Jun 2024

Editorial: Precision medicine: recent advances, current challenges and future perspectives

in Pharmacogenetics and Pharmacogenomics

Oriana Awwad
Mamoun Ahram
Francesca Coperchini
Mariam Abdel Jalil

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1439276

1,913 views
3 citations