Frontiers in Pharmacology | Pharmacology of Anti-Cancer Drugs

Case Report

Published on 06 Jan 2026

Hematologic immune-related adverse events in skin cancer patients treated with immune checkpoint inhibitors: a case series

in Pharmacology of Anti-Cancer Drugs

Rosa Falcone
Alessandra Frezzolini
Emanuele Bruni
Sofia Verkhovskaia
Maria Luigia Carbone
Francesca Romana Di Pietro
Paolo Chesi
Gabriele Piesco
Maria Cantonetti
Paolo Marchetti

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1717727

201 views

Review

Published on 06 Jan 2026

Fibroblast growth factor receptor inhibitors in glioma: a narrative review of recent advances

in Pharmacology of Anti-Cancer Drugs

Mingyu Han
Zhaokai Zhou
Bi Qian
Qiyuan Zhang
Cheng Peng
Fu Peng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1714696

108 views

Mini Review

Published on 06 Jan 2026

AI-driven immunotherapy: synergizing with radiotherapy to reconfigure the tumor microenvironment and treatment landscape

in Pharmacology of Anti-Cancer Drugs

Dongling Gu
Yi Feng
Hongyan Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1747638

109 views

Original Research

Published on 06 Jan 2026

Identification of novel germline and somatic mutations associated with hepatocellular carcinoma by next-generation sequencing

in Pharmacology of Anti-Cancer Drugs

Ahmed Baligh Laaribi
Wafa Babay
Abdelmalek Lekired
Bochra Bouchabou
Asma Mehri
Dhouha Bacha
Riadh Sassi
Sana Ben Slama
Rached Bayar
Sahir Omrani

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1699280

196 views

Original Research

Accepted on 05 Jan 2026

Paclitaxel-Induced Germline DNA-Damage Signatures Independent of Mismatch Repair in C. elegans

in Pharmacology of Anti-Cancer Drugs

Yebin Hong
Zifei Liu
Hyun-Min Kim

Frontiers in Pharmacology

Original Research

Published on 05 Jan 2026

Genome-wide CRISPR screen identified NEK6 as a determinant of sensitivity to CDK4/6 inhibitor in endometrial cancer

in Pharmacology of Anti-Cancer Drugs

Fangfang Jian
Chongying Zhu
Yiwei Wang
Tianyu Zhou
Chenmin Yang
Weiwei Feng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1725886

154 views

Original Research

Published on 05 Jan 2026

Cost-effectiveness analysis of inavolisib combined with palbociclib plus fulvestrant in PIK3CA-mutated HR+/Her2− advanced breast cancer in China

in Pharmacology of Anti-Cancer Drugs

Weiwei Huang
Cijuan Li
Yuanqing Huang
Chang Wang
Yingxin Zhang
Yingtao Lin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1742507

214 views

Mini Review

Published on 05 Jan 2026

Patient-derived organoids in non-small cell lung cancer: advances in drug sensitivity testing

in Pharmacology of Anti-Cancer Drugs

Wanyu Tang
Xudong Tian

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1639268

513 views

Case Report

Published on 05 Jan 2026

Molecular guided therapy leading to exceptional response in relapsed osteosarcoma

in Pharmacology of Anti-Cancer Drugs

Elizabeth Wert
Leah Menachery
Jeremy Hengst
Tarlan Arjmandi
Abhinav B. Nagulapally
Divya Gandra
Valerie Brown
Giselle Saulnier Sholler
Smita Dandekar

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1719832

295 views

Original Research

Accepted on 30 Dec 2025

Real-World Safety Profile and Mechanistic Insights into Regorafenib-Induced Liver Failure: A Pharmacovigilance Study Integrated with Network Toxicology

in Pharmacology of Anti-Cancer Drugs

Haonan Sun
Heng Gu
Pengkai Xu
Dong Jiang
Tian Pu
Jiangming Chen
Fubao Liu

Frontiers in Pharmacology

123 views

Original Research

Accepted on 29 Dec 2025

Pemetrexed sensitizes cisplatin therapy by inducing ferroptosis in NSCLC cells

in Pharmacology of Anti-Cancer Drugs

Yumin Wang
Xin Zhang
Yuwei Cao
Ge Zhang
Yonglin Zhu
Yulin Li
Jichao Chen

Frontiers in Pharmacology

Editorial

Accepted on 29 Dec 2025

Editorial: Combination Therapies in Cancer Treatment: Enhancing Efficacy and Reducing Resistance

in Pharmacology of Anti-Cancer Drugs

Xinyu Wang
Milica Pešić
Ana Podolski-Renic

Frontiers in Pharmacology

185 views

Editorial

Accepted on 29 Dec 2025

Editorial: Novel Therapeutics for Urological Cancers

in Pharmacology of Anti-Cancer Drugs

Shuai Tang
Benyi Li

Frontiers in Pharmacology

176 views

Review

Accepted on 29 Dec 2025

The ubiquitination–autophagy axis in cancer therapy resistance: mechanistic insights and therapeutic opportunities

in Pharmacology of Anti-Cancer Drugs

Hengrui Zhang
Hanxi Yan
Yulin Liu
Anqi Zeng
Linjiang Song

Frontiers in Pharmacology

Original Research

Accepted on 26 Dec 2025

Antitumor effects of LPM5140276 and its potential combination with SHP2 inhibition in KRASG12D-mutant cancer

in Pharmacology of Anti-Cancer Drugs

Zhengping Hu
Fangxia Zou
Pengfei Yu
Haibo Zhu
Jiajing Zhang
Liting Yu
Wenyan Wang
Liang Ye

Frontiers in Pharmacology

104 views

Original Research

Accepted on 25 Dec 2025

Association of Genetically Instrumented HMGCR Inhibition with the Therapeutic Role of Prostate Cancer: A Mendelian Randomization Study and Supporting in Vitro Experiments

in Pharmacology of Anti-Cancer Drugs

Xiaojie Hao
Jingjun Mu

Frontiers in Pharmacology

Original Research

Accepted on 25 Dec 2025

Serine synthesis and transport mediate the synergistic and detoxifying effects of lienal peptides on cisplatin

in Pharmacology of Anti-Cancer Drugs

Ke Ding
Tengjie Yu
Xiaowei Zhang
Kangrui Hu
Shuying Mao
Tingting Zhang
Ye Liu
Zhongbo Wang
Xin Fan
Wei Liu

Frontiers in Pharmacology

107 views

Review

Accepted on 24 Dec 2025

Novel Therapeutic Strategies Targeting Resistance Mechanisms in Hematologic Malignancies: From BCL2 Inhibition to Immunomodulatory Approaches

in Pharmacology of Anti-Cancer Drugs

Qianyu Han
Shasha Jiang
Jirui Chen
Lei Xue

Frontiers in Pharmacology

Editorial

Accepted on 23 Dec 2025

Editorial: Genomic Discoveries and Pharmaceutical Development in Urologic Tumors – Volume II

in Pharmacology of Anti-Cancer Drugs

Lei Yin
Wenjia Li
Jialin Meng
Huan Yang
tao zhang

Frontiers in Pharmacology

173 views

Review

Accepted on 22 Dec 2025

Spatial Profiling of the Metabolism-Immune Axis in Ovarian Cancer

in Pharmacology of Anti-Cancer Drugs

Zhi-Bin Wang
Ming-Hui Long
Ya -Li Wang
Zheng Yang
Masha Huang

Frontiers in Pharmacology

155 views

Original Research

Published on 19 Dec 2025

Multilocus inherited neoplasia allele syndrome (MINAS) in a Turkish cohort: molecular insights and clinical relevance for precision oncology

in Pharmacology of Anti-Cancer Drugs

Taha Bahsi
Serhat Seyhan
Kaan Helvaci
Umut Demirci
Irem Bilgetekin
Selami Bayram
Mehmet Akif Ozturk
Fatih Aydogan
Serkan Keskin
Kezban Pilanci

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1672774

1,000 views

Case Report

Published on 19 Dec 2025

Case Report: Tislelizumab–induced panuveitis: a report of two cases

in Pharmacology of Anti-Cancer Drugs

Huan Ding
Shuyuan Zhang
Lin Lin
Kaiyan Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1678663

830 views

Systematic Review

Published on 19 Dec 2025

Efficacy and safety of later-line targeted therapies in advanced non-small cell lung cancer with EGFR exon 20 insertion mutations: a systematic review

in Pharmacology of Anti-Cancer Drugs

Qiang Wen
Yue Zhuang
Silv Fu
Chunguo Pan
Zhihua Liu
Lei Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1707050

1,428 views

Original Research

Published on 18 Dec 2025

Multimode MALDI-MSI deciphers matrine-induced metabolic reprogramming in prostate cancer xenografts: spatial mapping of low-molecular-weight compound alterations

in Pharmacology of Anti-Cancer Drugs

Jia Xu
Liang Qin
Xiao Liang
Lulu Chen
Juexin Wang
Hua Guo
Fengmei Wang
Ran Wu
Xiaojing An
Wenjuan Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1627864

495 views

3,092 articles

articles

Hematologic immune-related adverse events in skin cancer patients treated with immune checkpoint inhibitors: a case series

Fibroblast growth factor receptor inhibitors in glioma: a narrative review of recent advances

AI-driven immunotherapy: synergizing with radiotherapy to reconfigure the tumor microenvironment and treatment landscape

Identification of novel germline and somatic mutations associated with hepatocellular carcinoma by next-generation sequencing

Paclitaxel-Induced Germline DNA-Damage Signatures Independent of Mismatch Repair in C. elegans

Genome-wide CRISPR screen identified NEK6 as a determinant of sensitivity to CDK4/6 inhibitor in endometrial cancer

Cost-effectiveness analysis of inavolisib combined with palbociclib plus fulvestrant in PIK3CA-mutated HR+/Her2− advanced breast cancer in China

Patient-derived organoids in non-small cell lung cancer: advances in drug sensitivity testing

Molecular guided therapy leading to exceptional response in relapsed osteosarcoma

Real-World Safety Profile and Mechanistic Insights into Regorafenib-Induced Liver Failure: A Pharmacovigilance Study Integrated with Network Toxicology

Pemetrexed sensitizes cisplatin therapy by inducing ferroptosis in NSCLC cells

Editorial: Combination Therapies in Cancer Treatment: Enhancing Efficacy and Reducing Resistance

Editorial: Novel Therapeutics for Urological Cancers

The ubiquitination–autophagy axis in cancer therapy resistance: mechanistic insights and therapeutic opportunities

Antitumor effects of LPM5140276 and its potential combination with SHP2 inhibition in KRASG12D-mutant cancer

Association of Genetically Instrumented HMGCR Inhibition with the Therapeutic Role of Prostate Cancer: A Mendelian Randomization Study and Supporting in Vitro Experiments

Serine synthesis and transport mediate the synergistic and detoxifying effects of lienal peptides on cisplatin

Novel Therapeutic Strategies Targeting Resistance Mechanisms in Hematologic Malignancies: From BCL2 Inhibition to Immunomodulatory Approaches

Editorial: Genomic Discoveries and Pharmaceutical Development in Urologic Tumors – Volume II

Spatial Profiling of the Metabolism-Immune Axis in Ovarian Cancer

Multilocus inherited neoplasia allele syndrome (MINAS) in a Turkish cohort: molecular insights and clinical relevance for precision oncology

Case Report: Tislelizumab–induced panuveitis: a report of two cases

Efficacy and safety of later-line targeted therapies in advanced non-small cell lung cancer with EGFR exon 20 insertion mutations: a systematic review

Multimode MALDI-MSI deciphers matrine-induced metabolic reprogramming in prostate cancer xenografts: spatial mapping of low-molecular-weight compound alterations