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ORIGINAL RESEARCH article

Front. Psychiatry

Sec. Public Mental Health

This article is part of the Research TopicAdvances in the Psychiatric Perspective on the Relationship Between Mental Health in Population with Systemic Diseases: Mechanisms and Therapeutic InnovationsView all 3 articles

Nutritional status mediates the relationship between depression and mild cognitive impairment among Chinese community-dwelling older adults

Provisionally accepted
  • 1Shanghai University of Medicine and Health Sciences, Shanghai, China
  • 2Shanghai Jiao Tong University School of Medicine Affiliated Renji Hospital, Shanghai, China
  • 3Pujiang Community Health Service Center in Minhang District, Shanghai, China

The final, formatted version of the article will be published soon.

Background: Mild cognitive impairment (MCI) and depression are prominent public health concerns among older adults, closely linked to their nutritional status. Our study aimed to explore the association and mediation pathways involving depression, nutritional status, and MCI in this population. Methods: The study included 4799 community-dwelling Chinese older adults aged 60 years and older in Tianjin and Shanghai, China. We utilized the 30-item Geriatric Depression Scale (GDS-30) to assess depression presence and severity. A GDS-30 score ≥11 indicated the presence of depression. Participants were categorized by symptom severity: "None" (GDS-30<11), "Mild" (11≤GDS-30≤20), "Moderate to severe" (20

Keywords: Depression, mediatation, Mild Cognitive Impairment, Nutritional Status, older adults "Insert table 3 here" 3.2 Body Composition

Received: 12 Aug 2025; Accepted: 12 Jan 2026.

Copyright: © 2026 Chen, Han, Liang, Cao, Gao and Guo. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Qi Guo

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