ORIGINAL RESEARCH article
Front. Psychiatry
Sec. Personality Disorders
This article is part of the Research TopicBorderline Personality Disorder: Insights into Etiology, Diagnosis, and Treatment StrategiesView all 7 articles
Real-World Outcomes of Mentalization-Based Therapy and Dialectical Behavior Therapy for Cluster B Personality Disorders: A Naturalistic Study of Hospital Service Use and Treatment Dropout
Provisionally accepted- 1université de montréal, Montreal, Canada
- 2University Institute in Mental Health of Montreal, Montreal, Canada
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Mentalization-based therapy (MBT) and dialectical behavior therapy (DBT) are effective treatments for cluster B personality disorders (PDs), but few studies have assessed their real-world clinical outcomes in routine practice outside a controlled trial setting. Our descriptive naturalistic retrospective study evaluated 288 patients with cluster B PDs who predominantly had borderline PD referred to MBT or DBT. Observed changes in emergency department (ED) use and hospitalizations one year before and during the first year of therapy were described for patients with at least one relevant event, along with dropout rates. ED visit analyses concerned 104 patients, and hospitalization analyses concerned 30 patients. Across both treatment modalities, ED visits decreased from 119 in the year prior to treatment to 37 during the first year of treatment (p < .001 for both). Hospitalizations were observed to decrease for patients in MBT (p < .05), while no clear change was seen in the DBT group (p = .595). Drop-out rates during treatment were around 30% in both modalities. These patterns descriptively suggest that both therapies are associated with reduced service use during treatment in clinical practice. Future research should investigate which patient- and system-level characteristics can guide patients and clinicians toward the most suitable treatment for each individual, and whether these observed patterns persist beyond the treatment period.
Keywords: Borderline, Cluster B, dialectical behavior therapy, mentalization-based therapy, Personality Disorders, Psychotherapy
Received: 27 Oct 2025; Accepted: 10 Feb 2026.
Copyright: © 2026 Yin, Poirier, Allary, Pérusse, David, Lahaie and Cailhol. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Lionel Cailhol
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