Frontiers in Psychiatry | Mood Disorders

Original Research

Published on 03 Feb 2026

Effects of exercise supplementary to standard therapy on cognition and sleep in depression: a randomised controlled trial

in Mood Disorders

Cong Liu
Fei Zhai
Min Li
Huiying Wang
Jianhong Zhang
Ziyang Ji
Hengfen Li

Frontiers in Psychiatry

doi 10.3389/fpsyt.2026.1650334

212 views

Original Research

Accepted on 02 Feb 2026

Divergent Pathways to Depression: A Network Analysis of Adverse Childhood Experiences in Migrant and Non-Migrant Youth

in Mood Disorders

Cihang Liu
Xinze Liu
Shujian WANG

Frontiers in Psychiatry

Clinical Trial

Accepted on 02 Feb 2026

Effects of in vitro fermentation of Astragalus polysaccharide on gut microbiota and neurotransmitter metabolites in patients with major depressive disorder

in Mood Disorders

Chen Lin
Yuwei Mi
HuoWang Zheng
Yanbin Hou
Jieqiong Hu
JiaXin Mao
Ni Dai
ChaoLang Fu
XiaoQiong Li
YunXin Ji

Frontiers in Psychiatry

Review

Published on 02 Feb 2026

Inflammatory models of depression in rodents and humans

in Mood Disorders

Dmitrii D. Markov
Svetlana A. Zozulya
Oleg V. Dolotov

Frontiers in Psychiatry

doi 10.3389/fpsyt.2026.1687579

272 views

Original Research

Published on 02 Feb 2026

A dual-path mediation model: associations between childhood psychological maltreatment and loneliness among Chinese college students

in Mood Disorders

Zihan Zhou
Mingbo Liu
Liang Chen

Frontiers in Psychiatry

doi 10.3389/fpsyt.2026.1747337

203 views

Original Research

Accepted on 30 Jan 2026

Gut Microbiota and Metabolic Characteristics in Subthreshold Depression Based on Multi-Omics

in Mood Disorders

Jin Xian
Ling Wang
RuPing Shang
Mi Sun
Xin Zhang
Hui-Juan Yu
Cheng Bin
Shi-Jun Wang
Qi-wen Tan

Frontiers in Psychiatry

165 views

Original Research

Published on 30 Jan 2026

Optimal GRID-HAM-D7 cut-off scores for defining remission in older Thai adults with depression

in Mood Disorders

Nahathai Wongpakaran
Rewadee Jenraumjit
Peerasak Lerttrakarnnon
Thanitha Siriruk
Nopporn Tantirangsee
Rob van Reekum
Tinakon Wongpakaran

Frontiers in Psychiatry

doi 10.3389/fpsyt.2026.1678542

343 views

Original Research

Accepted on 29 Jan 2026

More optimistic treatment expectations are associated with better outcomes through stronger group cohesion, but not dyadic alliance: Results from a naturalistic day clinic study in complex depression

in Mood Disorders

Catherine Irniger
Johannes Vetter
Steffi Weidt
Erich Seifritz
Martin grosse Holtforth
Rainer Krähenmann

Frontiers in Psychiatry

Clinical Trial

Accepted on 29 Jan 2026

Olink proteomics identifies FGF-19 as a treatment-responsive inflammatory biomarker associated with acupuncture intervention in young females with mild depression

in Mood Disorders

Zhongxian LI
Zitong Jiao
Min Peng
Pan Zhang
Haiyan Xu
Ruiming Chen
Qiaoyu Ji
Jingjing Li
Lihua Chen
Beibei Zhao

Frontiers in Psychiatry

158 views

Review

Published on 29 Jan 2026

Efficacy effects of fecal microbiota transplantation on depressive symptoms: a meta-analysis based on randomized controlled trials

in Mood Disorders

Jiamin Fu
Yuchi Zhang
Jing Gao
Ming Lan
Zhixin Zhang
Ruiting Liang
Hongyun Zhou
Shirui Liu
Ziyi Zhou
Jinwan Zhao

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1629290

514 views

Original Research

Published on 29 Jan 2026

The therapeutic potential of ayahuasca in depression, generalized anxiety, and substance use disorders: modulation of the depressive burden in a longitudinal study

in Mood Disorders

Gláucio Silva Camargos
Geraldo Magela de Faria Júnior
Marcelo Lourenço
Gerardo Maria de Araújo Filho

Frontiers in Psychiatry

doi 10.3389/fpsyt.2026.1726909

777 views

Original Research

Published on 29 Jan 2026

CD4+ T cell dysregulation in major depressive disorder is associated with sleep disturbance

in Mood Disorders

Yao Gao
Zihan Lei
Yifan Ren
Xianyan Zhan
Zirong Chen
Zuer Guo
Ziyang Zhou
Xiancang Ma
Pan Li

Frontiers in Psychiatry

doi 10.3389/fpsyt.2026.1763750

343 views

Original Research

Accepted on 28 Jan 2026

Machine Learning Framework for Depression Subtype Grouping: Integrating High-Resolution Imaging and Clinical Symptom Analysis via Correlation and Clustering

in Mood Disorders

Gaurav Verma
Yael Jacob
Laurel Morris
Xin Xing
Ai-Ling Lin
James Murrough
Priti Balchandani
Bradley N Delman

Frontiers in Psychiatry

107 views

Original Research

Published on 28 Jan 2026

The triglyceride-glucose index in relation to psychotic symptoms in adolescents with major depressive disorder

in Mood Disorders

Yi Tang
Wen Wu
Yun Zhang
Ji Yin
Dan Luo
Zhangyan Zhou
Hansong Xu

Frontiers in Psychiatry

doi 10.3389/fpsyt.2026.1755283

387 views

Correction

Published on 28 Jan 2026

Correction: Toward precision psychological rehabilitation: predicting CBT efficacy in post-stroke depression using machine learning

in Mood Disorders

Jingyuan Lin
Jiansong Yu

Frontiers in Psychiatry

doi 10.3389/fpsyt.2026.1787831

252 views

Systematic Review

Accepted on 27 Jan 2026

Effect of Non-Pharmacological Interventions on Depression in Obese Individuals: A Network Meta-Analysis

in Mood Disorders

Zhilin Chen
Ruiqing Wang
Yiwei Wang
Yangpu Zhang
Aiqun Song

Frontiers in Psychiatry

122 views

Original Research

Accepted on 27 Jan 2026

Episode-wide Maudsley staging in treatment-resistant depression: a longitudinal tertiary-care comparison of dimensional and categorical outcomes

in Mood Disorders

Anastasia Antoniou
Sofia Pappa
Dimitrios Dikeos
Nikolaos Smyrnis
Julien Mendlevicz
Alessandro Serretti
Anthony Cleare
Panagiotis Ferentinos

Frontiers in Psychiatry

154 views

Original Research

Accepted on 27 Jan 2026

Prediction of Suicide Attempts in Depressive Disorder and Panic Disorder With/Without Agoraphobia: Multivariate Analysis of Clinical Predictors

in Mood Disorders

Borjanka Batinic
Barbara Kecman
Goran Opacic
Matej Stuhec

Frontiers in Psychiatry

Original Research

Accepted on 26 Jan 2026

Mental Health Professionals' Perspective on the Use of Esketamine in Treatment-Resistant Depression and Their Motivation to Adopt It: A Saudi Cross-sectional Study

in Mood Disorders

Ahmad H. Almadani
Ayedh H. Alghamdi
Gosay M. Almazyad
Saleh I. Alfawaz
Mohammed A. Ghaith
Ali A. Alshehri
Mohammed A. Aljaffer
Saleh A. Alghamdi

Frontiers in Psychiatry

147 views

Systematic Review

Accepted on 26 Jan 2026

Association between maternal depressive symptoms during pregnancy and the risk of preeclampsia: a meta-analysis

in Mood Disorders

Caixia Yi
Peiyu Cheng
Ning Peng
Yao Su
Huan Cao
Fangqun Cheng

Frontiers in Psychiatry

Original Research

Accepted on 26 Jan 2026

The Role of Hypothyroidism in the resilience against depressive Episodes during covid pandemic in a Cohort of old adults

in Mood Disorders

Alessandra Perra
Massimo Tusconi
Elisa Cantone
Michela Atzeni
Enzo Tramontano
Stefano Lorrai
Fabrizio Bert
Antonio E Nardi
Mauro Giovanni Carta
Giulia Cossu

Frontiers in Psychiatry

200 views

Opinion

Accepted on 26 Jan 2026

Psychosomatics at the Threshold: Cancer, Mood Disorders, and the Mental Pain of Death Where precision medicine meets spirituality

in Mood Disorders

Mauro Giovanni Carta
Antonio E Nardi

Frontiers in Psychiatry

156 views

Original Research

Accepted on 22 Jan 2026

Disrupted rich club organization in structural brain networks is related to childhood maltreatment in major depressive disorder

in Mood Disorders

Junhua Huang
Bei Rong
Guoqing Gao
Mingzhe Zhou
Haomian Zhao
Yu Gao
Ning Tu
Lihong Bu
Ling Xiao
Gaohua Wang

Frontiers in Psychiatry

114 views

Original Research

Published on 22 Jan 2026

Prevalence and factors associated with mental distress among men at higher risk of HIV infection enrolled in an HIV pre-exposure prophylaxis program in Tanga, Tanzania

in Mood Disorders

Nuruel Robert Kitomary
Emmy Metta
Melkizedeck T. Leshabari
Kåre Moen
Elia J. Mmbaga

Frontiers in Psychiatry

doi 10.3389/fpsyt.2026.1605734

338 views

1,705 articles

articles

Effects of exercise supplementary to standard therapy on cognition and sleep in depression: a randomised controlled trial

Divergent Pathways to Depression: A Network Analysis of Adverse Childhood Experiences in Migrant and Non-Migrant Youth

Effects of in vitro fermentation of Astragalus polysaccharide on gut microbiota and neurotransmitter metabolites in patients with major depressive disorder

Inflammatory models of depression in rodents and humans

A dual-path mediation model: associations between childhood psychological maltreatment and loneliness among Chinese college students

Gut Microbiota and Metabolic Characteristics in Subthreshold Depression Based on Multi-Omics

Optimal GRID-HAM-D7 cut-off scores for defining remission in older Thai adults with depression

More optimistic treatment expectations are associated with better outcomes through stronger group cohesion, but not dyadic alliance: Results from a naturalistic day clinic study in complex depression

Olink proteomics identifies FGF-19 as a treatment-responsive inflammatory biomarker associated with acupuncture intervention in young females with mild depression

Efficacy effects of fecal microbiota transplantation on depressive symptoms: a meta-analysis based on randomized controlled trials

The therapeutic potential of ayahuasca in depression, generalized anxiety, and substance use disorders: modulation of the depressive burden in a longitudinal study

CD4+ T cell dysregulation in major depressive disorder is associated with sleep disturbance

Machine Learning Framework for Depression Subtype Grouping: Integrating High-Resolution Imaging and Clinical Symptom Analysis via Correlation and Clustering

The triglyceride-glucose index in relation to psychotic symptoms in adolescents with major depressive disorder

Correction: Toward precision psychological rehabilitation: predicting CBT efficacy in post-stroke depression using machine learning

Effect of Non-Pharmacological Interventions on Depression in Obese Individuals: A Network Meta-Analysis

Episode-wide Maudsley staging in treatment-resistant depression: a longitudinal tertiary-care comparison of dimensional and categorical outcomes

Prediction of Suicide Attempts in Depressive Disorder and Panic Disorder With/Without Agoraphobia: Multivariate Analysis of Clinical Predictors

Mental Health Professionals' Perspective on the Use of Esketamine in Treatment-Resistant Depression and Their Motivation to Adopt It: A Saudi Cross-sectional Study

Association between maternal depressive symptoms during pregnancy and the risk of preeclampsia: a meta-analysis

The Role of Hypothyroidism in the resilience against depressive Episodes during covid pandemic in a Cohort of old adults

Psychosomatics at the Threshold: Cancer, Mood Disorders, and the Mental Pain of Death Where precision medicine meets spirituality

Disrupted rich club organization in structural brain networks is related to childhood maltreatment in major depressive disorder

Prevalence and factors associated with mental distress among men at higher risk of HIV infection enrolled in an HIV pre-exposure prophylaxis program in Tanga, Tanzania