Frontiers in Psychiatry | Mood Disorders

Clinical Trial

Published on 11 Feb 2026

The effect of bright light therapy on glycemic control and cortisol rhythmicity in depression: a randomized controlled trial

in Mood Disorders

Jie Fang
Xinyu Li
Shukun Zhu
Qinghong Hu
Ting Wang
Jiakuai Yu
Ximing Qin
Daomin Zhu

Frontiers in Psychiatry

doi 10.3389/fpsyt.2026.1743465

338 views

Original Research

Published on 11 Feb 2026

Episode-wide Maudsley staging in treatment-resistant depression: a longitudinal tertiary-care comparison of dimensional and categorical outcomes

in Mood Disorders

Anastasia Antoniou
Sofia Pappa
Dimitrios Dikeos
Nikolaos Smyrnis
Julien Mendlevicz
Alessandro Serretti
Anthony Cleare
Panagiotis Ferentinos

Frontiers in Psychiatry

doi 10.3389/fpsyt.2026.1769246

409 views

Original Research

Accepted on 10 Feb 2026

Altered EEG Microstate Associated With Anxiety and Somatization Symptoms in Major Depressive Disorder

in Mood Disorders

qinfan Shan
Guisen Wu
Yuxuan Xiong
Qian Guo
Hao Hu
Fuxu Zhang
Zhenying Qian
Tianhong Zhang
Xiaohua Liu

Frontiers in Psychiatry

Original Research

Accepted on 10 Feb 2026

Inflammation–HDL Axis Indices Differentiate Bipolar Disorder From Healthy Controls: A Comparison of Drug-Naive First-Episode Mania and Euthymic Recurrent Patients

in Mood Disorders

Fatih Ekici
Rukiye Tekdemir
Ömer Bayırlı
Furkan Çınar
Mustafa Esad Tezcan

Frontiers in Psychiatry

Original Research

Published on 10 Feb 2026

Patient complexity profiles in depression: a machine learning approach to personalized mental health

in Mood Disorders

Paula Dagnino
Matias Salinas
Rodrigo Salas

Frontiers in Psychiatry

doi 10.3389/fpsyt.2026.1741860

271 views

Opinion

Published on 10 Feb 2026

Psychosomatics at the threshold: cancer, mood disorders, and the mental pain of death — where precision medicine meets spirituality

in Mood Disorders

Mauro Giovanni Carta
Antonio Egidio Nardi

Frontiers in Psychiatry

doi 10.3389/fpsyt.2026.1751310

287 views

Original Research

Accepted on 09 Feb 2026

Associations between self-management strategies and clinical outcomes in depression: a cross-sectional survey

in Mood Disorders

Teruo Tada
Hitoshi Sakurai
Taku Maruki
Masami Murao
Yasuyuki Matsumoto
Yumi Aoki
Hisateru Tachimori
Yayoi Imamura
Yu Matsumoto
Norifusa Sawada

Frontiers in Psychiatry

Original Research

Published on 09 Feb 2026

Low-grade inflammatory parameters may be associated with recent suicide attempts – a naturalistic study among psychiatric inpatients with depressive disorders

in Mood Disorders

Csenge Lovig
Peter Osvath
Eszter Saghy
Csilla Molnar
Marton Aron Kovacs
Borbala Petho
Diana Simon
Sandor Fekete
Tamas Tenyi
Viktor Voros

Frontiers in Psychiatry

doi 10.3389/fpsyt.2026.1707768

523 views

Original Research

Published on 05 Feb 2026

Efficacy and safety of toludesvenlafaxine hydrochloride sustained-release tablets in depression with ineffective or partially effective initial antidepressant treatment: a single-arm, multicenter clinical study

in Mood Disorders

Jingming Yang
Yanyan Jia
Ke Chen
Weiye Liang
Jing Long
Meijuan Li
Qianqian Wei
Jian Wang
Baoping Yan
Keqing Li

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1740789

674 views

Original Research

Accepted on 04 Feb 2026

Layered vulnerabilities in young adults with major depressive disorder: Personality, coping, and cognition

in Mood Disorders

Gabrielle Wann Nii Tay
Glenn Tze Yi Tay
Cyrus Su Hui Ho

Frontiers in Psychiatry

144 views

Original Research

Published on 04 Feb 2026

Deficit in attentional capture by social-value related conditioned stimuli — a new perspective to understand the social-reward learning disorders among individuals with depressive symptoms

in Mood Disorders

Jinsheng Hu
Xiaoning Zhao

Frontiers in Psychiatry

doi 10.3389/fpsyt.2026.1692037

283 views

Systematic Review

Published on 04 Feb 2026

Efficacy comparison of different external traditional Chinese medicine therapies as monotherapy or in combination for premenstrual syndrome: a systematic review and network meta-analysis

in Mood Disorders

Yuhong Xie
Jinying Zhao
Shuai Fan
Ning Yang
Huiying Liu
Yuwei Guo
Xu Feng
Ziheng Wang
Min Zhang
Fuchun Wang

Frontiers in Psychiatry

doi 10.3389/fpsyt.2026.1720232

474 views

Original Research

Accepted on 03 Feb 2026

Integrating Thyroid Function and Psychometric Profiles for Lifetime Suicide-Attempt Risk Stratification in Bipolar Disorder: A Multi-Algorithm Machine-Learning Study

in Mood Disorders

Boyu Zhang
Min Pan
Anzhen Wang
Wenmei Fang
Jianjun Guan
Zhiyong Li
夏龙程
Yu Xie

Frontiers in Psychiatry

109 views

Original Research

Accepted on 03 Feb 2026

Decoupling reveals subtypes of nonsuicidal self-injury

in Mood Disorders

Lan Hu
Kena Li
Hui He
Shaoqing Li
Nan Qiu
Guocheng Zhao
Tingyu Hu
Yong Chen
Cheng Luo

Frontiers in Psychiatry

Original Research

Published on 03 Feb 2026

Effects of exercise supplementary to standard therapy on cognition and sleep in depression: a randomised controlled trial

in Mood Disorders

Cong Liu
Fei Zhai
Min Li
Huiying Wang
Jianhong Zhang
Ziyang Ji
Hengfen Li

Frontiers in Psychiatry

doi 10.3389/fpsyt.2026.1650334

469 views

Original Research

Accepted on 02 Feb 2026

Divergent Pathways to Depression: A Network Analysis of Adverse Childhood Experiences in Migrant and Non-Migrant Youth

in Mood Disorders

Cihang Liu
Xinze Liu
Shujian WANG

Frontiers in Psychiatry

Clinical Trial

Accepted on 02 Feb 2026

Effects of in vitro fermentation of Astragalus polysaccharide on gut microbiota and neurotransmitter metabolites in patients with major depressive disorder

in Mood Disorders

Chen Lin
Yuwei Mi
HuoWang Zheng
Yanbin Hou
Jieqiong Hu
JiaXin Mao
Ni Dai
ChaoLang Fu
XiaoQiong Li
YunXin Ji

Frontiers in Psychiatry

148 views

Review

Published on 02 Feb 2026

Inflammatory models of depression in rodents and humans

in Mood Disorders

Dmitrii D. Markov
Svetlana A. Zozulya
Oleg V. Dolotov

Frontiers in Psychiatry

doi 10.3389/fpsyt.2026.1687579

578 views

Original Research

Published on 02 Feb 2026

A dual-path mediation model: associations between childhood psychological maltreatment and loneliness among Chinese college students

in Mood Disorders

Zihan Zhou
Mingbo Liu
Liang Chen

Frontiers in Psychiatry

doi 10.3389/fpsyt.2026.1747337

331 views

Original Research

Accepted on 30 Jan 2026

Gut Microbiota and Metabolic Characteristics in Subthreshold Depression Based on Multi-Omics

in Mood Disorders

Jin Xian
Ling Wang
RuPing Shang
Mi Sun
Xin Zhang
Hui-Juan Yu
Cheng Bin
Shi-Jun Wang
Qi-wen Tan

Frontiers in Psychiatry

223 views

Original Research

Published on 30 Jan 2026

Optimal GRID-HAM-D7 cut-off scores for defining remission in older Thai adults with depression

in Mood Disorders

Nahathai Wongpakaran
Rewadee Jenraumjit
Peerasak Lerttrakarnnon
Thanitha Siriruk
Nopporn Tantirangsee
Rob van Reekum
Tinakon Wongpakaran

Frontiers in Psychiatry

doi 10.3389/fpsyt.2026.1678542

461 views

Original Research

Accepted on 29 Jan 2026

More optimistic treatment expectations are associated with better outcomes through stronger group cohesion, but not dyadic alliance: Results from a naturalistic day clinic study in complex depression

in Mood Disorders

Catherine Irniger
Johannes Vetter
Steffi Weidt
Erich Seifritz
Martin grosse Holtforth
Rainer Krähenmann

Frontiers in Psychiatry

112 views

Clinical Trial

Accepted on 29 Jan 2026

Olink proteomics identifies FGF-19 as a treatment-responsive inflammatory biomarker associated with acupuncture intervention in young females with mild depression

in Mood Disorders

Zhongxian LI
Zitong Jiao
Min Peng
Pan Zhang
Haiyan Xu
Ruiming Chen
Qiaoyu Ji
Jingjing Li
Lihua Chen
Beibei Zhao

Frontiers in Psychiatry

199 views

Review

Published on 29 Jan 2026

Efficacy effects of fecal microbiota transplantation on depressive symptoms: a meta-analysis based on randomized controlled trials

in Mood Disorders

Jiamin Fu
Yuchi Zhang
Jing Gao
Ming Lan
Zhixin Zhang
Ruiting Liang
Hongyun Zhou
Shirui Liu
Ziyi Zhou
Jinwan Zhao

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1629290

713 views

1,711 articles

articles

The effect of bright light therapy on glycemic control and cortisol rhythmicity in depression: a randomized controlled trial

Episode-wide Maudsley staging in treatment-resistant depression: a longitudinal tertiary-care comparison of dimensional and categorical outcomes

Altered EEG Microstate Associated With Anxiety and Somatization Symptoms in Major Depressive Disorder

Inflammation–HDL Axis Indices Differentiate Bipolar Disorder From Healthy Controls: A Comparison of Drug-Naive First-Episode Mania and Euthymic Recurrent Patients

Patient complexity profiles in depression: a machine learning approach to personalized mental health

Psychosomatics at the threshold: cancer, mood disorders, and the mental pain of death — where precision medicine meets spirituality

Associations between self-management strategies and clinical outcomes in depression: a cross-sectional survey

Low-grade inflammatory parameters may be associated with recent suicide attempts – a naturalistic study among psychiatric inpatients with depressive disorders

Efficacy and safety of toludesvenlafaxine hydrochloride sustained-release tablets in depression with ineffective or partially effective initial antidepressant treatment: a single-arm, multicenter clinical study

Layered vulnerabilities in young adults with major depressive disorder: Personality, coping, and cognition

Deficit in attentional capture by social-value related conditioned stimuli — a new perspective to understand the social-reward learning disorders among individuals with depressive symptoms

Efficacy comparison of different external traditional Chinese medicine therapies as monotherapy or in combination for premenstrual syndrome: a systematic review and network meta-analysis

Integrating Thyroid Function and Psychometric Profiles for Lifetime Suicide-Attempt Risk Stratification in Bipolar Disorder: A Multi-Algorithm Machine-Learning Study

Decoupling reveals subtypes of nonsuicidal self-injury

Effects of exercise supplementary to standard therapy on cognition and sleep in depression: a randomised controlled trial

Divergent Pathways to Depression: A Network Analysis of Adverse Childhood Experiences in Migrant and Non-Migrant Youth

Effects of in vitro fermentation of Astragalus polysaccharide on gut microbiota and neurotransmitter metabolites in patients with major depressive disorder

Inflammatory models of depression in rodents and humans

A dual-path mediation model: associations between childhood psychological maltreatment and loneliness among Chinese college students

Gut Microbiota and Metabolic Characteristics in Subthreshold Depression Based on Multi-Omics

Optimal GRID-HAM-D7 cut-off scores for defining remission in older Thai adults with depression

More optimistic treatment expectations are associated with better outcomes through stronger group cohesion, but not dyadic alliance: Results from a naturalistic day clinic study in complex depression

Olink proteomics identifies FGF-19 as a treatment-responsive inflammatory biomarker associated with acupuncture intervention in young females with mild depression

Efficacy effects of fecal microbiota transplantation on depressive symptoms: a meta-analysis based on randomized controlled trials