Frontiers in Systems Biology

Original Research

Published on 17 Oct 2025

Dietary composition and fasting regimens differentially impact the gut microbiome and short-chain fatty acid profile in a Pakistani cohort

Farzana Gul
Hilde Herrema
Aqsa Ameer
Mark Davids
Arshan Nasir
Konstantinos Gerasimidis
Umer Zeeshan Ijaz
Sundus Javed

Frontiers in Systems Biology

doi 10.3389/fsysb.2025.1622753

1,333 views

Original Research

Published on 14 Oct 2025

Aging and activity patterns: actigraphy evidence from NHANES studies

Wen Luo
Matthew T. Scharf
Ioannis P. Androulakis

Frontiers in Systems Biology

doi 10.3389/fsysb.2025.1632110

515 views

Correction

Accepted on 10 Oct 2025

Correction: A GUIDE TO BAYESIAN NETWORKS SOFTWARE FOR STRUCTURE AND PARAMETER LEARNING, WITH A FOCUS ON CAUSAL DISCOVERY TOOLS

Francesco Canonaco
Joverlyn Gaudillo
Nicole Astrologo
Fabio Stella
Enzo Acerbi

Frontiers in Systems Biology

doi 10.3389/fsysb.2025.1717030

224 views

Original Research

Accepted on 10 Oct 2025

The role of neutrophil‑to‑lymphocyte ratio in the prognosis of chronic kidney disease: insights from the NHANES cohort study

Ying Liu
Ru Wang
Jinguo Yuan
Jin Zhao

Frontiers in Systems Biology

doi 10.3389/fsysb.2025.1656683

100 views

Original Research

Published on 29 Sep 2025

GETgene-AI: a framework for prioritizing actionable cancer drug targets

Adrian Gu
Jake Y. Chen

Frontiers in Systems Biology

doi 10.3389/fsysb.2025.1649758

1,900 views

Correction

Accepted on 22 Sep 2025

Correction: MicrobiomeKG: bridging microbiome research and host health through knowledge graphs

Frontiers Production Office

Frontiers in Systems Biology

doi 10.3389/fsysb.2025.1710604

310 views

Hypothesis and Theory

Accepted on 19 Sep 2025

Structural properties and asymptotic behaviour of bacterial Two-Component Systems

Irene Zorzan
Chiara Cimolato
Luca Schenato
Massimo Bellato

Frontiers in Systems Biology

doi 10.3389/fsysb.2025.1693064

321 views

Original Research

Published on 15 Sep 2025

Digital patient modeling identifies predictive biomarkers of regorafenib response in elderly metastatic colorectal cancer

Juan Manuel García-Illarramendi
Pedro Matos-Filipe
Jose Manuel Mas
Judith Farrés
Xavier Daura

Frontiers in Systems Biology

doi 10.3389/fsysb.2025.1648559

1,204 views

Review

Published on 12 Sep 2025

Bridging academia and industry: advancing systems biology and QSP education through AstraZeneca’s collaborative partnerships

Cesar Pichardo-Almarza
Holly Kimko

Frontiers in Systems Biology

doi 10.3389/fsysb.2025.1627214

1,112 views

Original Research

Accepted on 03 Sep 2025

Toward Effective Cystic Fibrosis Gene Therapy by Optimizing Prime Editing and Pulmonary-Targeted LNPs

Kaya Sophie Lange
Lisa Marie Wiesner
Kathleen Susat
Vera Köhler
Malte Lenger
Christian Alexander Michalek
Philip Frederic Mundt
Anna-Lena Baack
Kai Kanthak
Isabell Alexandra Guckes

Frontiers in Systems Biology

doi 10.3389/fsysb.2025.1603749

492 views

Brief Research Report

Published on 29 Aug 2025

MicrobiomeKG: bridging microbiome research and host health through knowledge graphs

Skye L. Goetz
Amy K. Glen
Gwênlyn Glusman

Frontiers in Systems Biology

doi 10.3389/fsysb.2025.1544432

1,983 views
2 citations

Mini Review

Published on 25 Aug 2025

A guide to bayesian networks software for structure and parameter learning, with a focus on causal discovery tools

Francesco Canonaco
Joverlyn Gaudillo
Nicole Astrologo
Fabio Stella
Enzo Acerbi

Frontiers in Systems Biology

doi 10.3389/fsysb.2025.1631901

1,976 views

Methods

Published on 22 Aug 2025

From flux analysis to self contained cellular models

Andreas Kremling

Frontiers in Systems Biology

doi 10.3389/fsysb.2025.1546072

1,176 views
1 citation

Original Research

Published on 14 Aug 2025

A model-based design strategy to engineer miRNA-regulated detection systems

Renske J. Verkuijlen
Robert W. Smith

Frontiers in Systems Biology

doi 10.3389/fsysb.2025.1601854

1,243 views

Review

Published on 08 Aug 2025

Unraveling the role of mobile genetic elements in antibiotic resistance transmission and defense strategies in bacteria

Ranjith Kumavath
Puja Gupta
Eswar Rao Tatta
Mahima S. Mohan
Simi Asma Salim
Siddhardha Busi

Frontiers in Systems Biology

doi 10.3389/fsysb.2025.1557413

2,670 views
1 citation

Original Research

Published on 30 Jul 2025

A Pseudomonas fluorescens AND-gate biosensor for protein expression at plant root proximity

Nico van Donk
Antoine Raynal
Enrique Asin-Garcia

Frontiers in Systems Biology

doi 10.3389/fsysb.2025.1620608

1,837 views

165 Publications

Volume 5 - 2025

Dietary composition and fasting regimens differentially impact the gut microbiome and short-chain fatty acid profile in a Pakistani cohort

Aging and activity patterns: actigraphy evidence from NHANES studies

Correction: A GUIDE TO BAYESIAN NETWORKS SOFTWARE FOR STRUCTURE AND PARAMETER LEARNING, WITH A FOCUS ON CAUSAL DISCOVERY TOOLS

The role of neutrophil‑to‑lymphocyte ratio in the prognosis of chronic kidney disease: insights from the NHANES cohort study

GETgene-AI: a framework for prioritizing actionable cancer drug targets

Correction: MicrobiomeKG: bridging microbiome research and host health through knowledge graphs

Structural properties and asymptotic behaviour of bacterial Two-Component Systems

Digital patient modeling identifies predictive biomarkers of regorafenib response in elderly metastatic colorectal cancer

Bridging academia and industry: advancing systems biology and QSP education through AstraZeneca’s collaborative partnerships

Toward Effective Cystic Fibrosis Gene Therapy by Optimizing Prime Editing and Pulmonary-Targeted LNPs

MicrobiomeKG: bridging microbiome research and host health through knowledge graphs

A guide to bayesian networks software for structure and parameter learning, with a focus on causal discovery tools

From flux analysis to self contained cellular models

A model-based design strategy to engineer miRNA-regulated detection systems

Unraveling the role of mobile genetic elements in antibiotic resistance transmission and defense strategies in bacteria

A Pseudomonas fluorescens AND-gate biosensor for protein expression at plant root proximity