About this Research Topic
Despite such progress, much remains unknown. For example, it is not clear what drives subgingival microbial dysbiosis. Furthermore, the functional and metabolic changes in subgingival microbiome and how they interact with the host immune response to induce periodontitis are not well understood. Moreover, the potential role of microbes other than bacteria in pathogenesis of periodontitis remains unclear. In addition, information about how subgingival microbiota affect systemic health is limited. This Research Topic aims to address these gaps.
We welcome all submissions, including research articles, reviews, perspective articles, meta-analyses, mini-reviews, opinion articles, and short communications, providing new insights into the microbiology of periodontitis. Studies of interest include, but are not limited to:
- High resolution (strain-level), functional, and/or metabolic characterization of the subgingival microbiome by integration of advanced omics techniques.
- The role of virome, mycobiome and interkingdom interactions in periodontitis
- Mechanistic studies on more recently discovered periodontal pathogens and their interactions with the host.
- Investigations into the association of periodontal microbiome with systemic diseases, including oral-gut axis.
- In vitro, animal or human studies to identify the drivers of subgingival microbiome
- Studies on the subgingival microbiome in unique populations or rare forms of periodontitis.
- Effects of novel therapeutics, including microbiome modulators, on the subgingival microbiome
Keywords: Microbiology, Periodontitis, subgingival, biofilm, microbiome, microbiota, bacteria, fungi, viruses, dysbiosis, immunity, oral-gut axis
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.