Advancing Multidisciplinary Approaches in Skull-Base Tumor Management

Skull-base tumors, a subset of neoplasms, present a formidable challenge in the field of oncology due to their complex anatomical location at the interface of the brain and skull-base. These tumors can originate from a variety of cell types, including those of the brain, nerves, bones, or surrounding tissues, resulting in a diverse and intricate classification. Their proximity to critical structures such as cranial nerves, major blood vessels, and vital sensory organs often leads to a wide range of clinical manifestations, including neurological deficits and sensory disturbances. The complexity of their anatomical location makes surgical resection particularly challenging, necessitating a multidisciplinary approach for optimal management. Recent advances in imaging, surgical techniques, radiation therapy, and systemic treatments have significantly improved diagnostic accuracy and therapeutic outcomes. However, there remains a need for further research to enhance our understanding and refine the multidisciplinary strategies essential for effectively managing these intricate malignancies.

This research topic aims to explore the multidisciplinary management of skull-base tumors, focusing on enhancing our understanding and refining strategies to tackle these complex malignancies. The primary objectives include investigating innovative surgical techniques, advancements in radiation therapy, the role of systemic therapies, and the integration of advanced imaging modalities. By addressing these areas, the research seeks to optimize patient outcomes and improve the overall management of skull-base tumors.

To gather further insights into the multidisciplinary management of skull-base tumors, we welcome articles addressing, but not limited to, the following themes:
- Surgical Innovations: Cutting-edge surgical techniques and technologies that enhance precision and minimize morbidity in skull-base tumor resections.
- Radiation Therapy Strategies: Latest developments in radiation therapy modalities, including proton therapy and stereotactic radiosurgery.
- Medical Oncology Advancements: The role of systemic therapies, including targeted therapies and immunotherapies, in the management of skull-base tumors.
- Imaging and Diagnostic Modalities: Advancements in imaging techniques for accurate diagnosis, preoperative planning, and post-treatment surveillance.
- Multidisciplinary Collaboration: The importance of collaborative efforts among various specialties in providing comprehensive care for patients with skull-base tumors.
Please note: Manuscripts consisting solely of bioinformatics, computational analysis, or predictions of public databases which are not accompanied by validation (independent clinical or patient cohort, or biological validation in vitro or in vivo, which are not based on public databases) are not suitable for publication in this journal.

Keywords: Skull base neoplasm, carcinoma, personalized medicine, paranasal sinus, Central Nervous System Neoplasms, Cranial Nerve Disorders, Neuroendoscopy

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.