The Impact of GIP/GIPR on Metabolic Diseases: How the Field Is Evolving

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Articles

EDITORIAL

Accepted on 02 Oct 2025

Exploring the expanding therapeutic value of glucose-dependent insulinotropic polypeptide receptor signaling. An editorial for "The Impact of GIP/GIPR on Metabolic Diseases: How the Field Is Evolving"

Kirk M. Habegger
Alejandra Tomas
Roger Chen
Charles Harris
William C Roell
Tamer Coskun

doi 10.3389/fendo.2025.1710843

412 views

ORIGINAL RESEARCH

Published on 02 Sep 2025

Counterregulatory response to hypoglycemia during a hypoglycemic clamp in people with type 2 diabetes treated with tirzepatide

Thomas R. Pieber
Eva Svehlikova
Shweta Urva
Axel Haupt
Chunmei Zhou
Tamer Coskun
Vera Höller
Gabriele Fluhr
Chrisanthi A. Karanikas
1 more
Edward John Pratt

doi 10.3389/fendo.2025.1627947

1,452 views

REVIEW

Published on 21 May 2025

The evolution of the therapeutic concept ‘GIP receptor antagonism’

Frederikke Koefoed-Hansen
Mads Marstrand Helsted
Hüsün Sheyma Kizilkaya
Asger Bach Lund
Mette Marie Rosenkilde
Lærke Smidt Gasbjerg

doi 10.3389/fendo.2025.1570603

3,478 views
2 citations

REVIEW

Published on 17 Mar 2025

The role of GIPR in food intake control

Paula-Peace James-Okoro
Jo Edward Lewis
Fiona Mary Gribble
Frank Reimann

doi 10.3389/fendo.2025.1532076

4,994 views
1 citation

REVIEW

Published on 03 Feb 2025

The agony and the efficacy: central mechanisms of GLP-1 induced adverse events and their mitigation by GIP

Jonathan D. Douros
Jonathan N. Flak
Patrick J. Knerr

doi 10.3389/fendo.2025.1530985

3,087 views
3 citations

REVIEW

Published on 24 Jul 2024

Mechanisms of action and therapeutic applications of GLP-1 and dual GIP/GLP-1 receptor agonists

Qiyuan Keith Liu

doi 10.3389/fendo.2024.1431292

48,887 views
73 citations

REVIEW

Published on 24 Jun 2024

Tirzepatide against obesity and insulin-resistance: pathophysiological aspects and clinical evidence

Salvatore Corrao
Chiara Pollicino
Dalila Maggio
Alessandra Torres
Christiano Argano

doi 10.3389/fendo.2024.1402583

13,536 views
18 citations

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Frontiers in Endocrinology

Frontiers in Endocrinology

Diabetes: Molecular Mechanisms

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