Advancements in Understanding and Managing Preeclampsia: Exploring Molecular Mechanisms, Biomarkers, and Clinical Implications

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ORIGINAL RESEARCH

Published on 31 Jul 2025

Molecular signatures of preeclampsia subtypes determined through integrated weighted gene co-expression network analysis and differential gene expression analysis of placental transcriptomics

Luhao Han
Fabricio da Silva Costa
Anthony Perkins
Olivia Holland

doi 10.3389/fcell.2025.1635878

248 views

ORIGINAL RESEARCH

Published on 17 Jul 2025

Multiple analytical perspectives of mitochondrial genes in the context of preeclampsia: potential diagnostic markers

Can Li
Fang Liu
Chao Li
Xiangzhong Zhao
Qiulan Lv
Aiping Jiang
Shuping Zhao

doi 10.3389/fimmu.2025.1595706

625 views

ORIGINAL RESEARCH

Published on 02 Jul 2025

Prediction and immune landscape study of potentially key autophagy-related biomarkers in preeclampsia with gestational diabetes mellitus

Qin Wang
Xiaoqi Li
Wen Ye
Lin Lin
Kejun Ye
Mengjia Peng

doi 10.3389/fimmu.2025.1571795

1,938 views

ORIGINAL RESEARCH

Published on 02 Apr 2025

BNIP3-mediated mitophagy aggravates placental injury in preeclampsia via NLRP1 inflammasome

Man Zhao
Zexin Yang
Yan Kang
Zhenya Fang
Changqing Zhang
Chunying Wang
Meijuan Zhou
Junjun Guo
Anna Li
Meihua Zhang

doi 10.3389/fimmu.2025.1530015

1,784 views

ORIGINAL RESEARCH

Published on 28 Feb 2025

Evaluating oxidative stress targeting treatments in in vitro models of placental stress relevant to preeclampsia

Dinara Afrose
Matt D. Johansen
Valentina Nikolic
Natasa Karadzov Orlic
Zeljko Mikovic
Milan Stefanovic
Zoran Cakic
Philip M. Hansbro
Lana McClements

doi 10.3389/fcell.2025.1539496

2,051 views
1 citation

REVIEW

Published on 07 Feb 2025

Secondary prevention of preeclampsia

Muhammad Ilham Aldika Akbar
Roudhona Rosaudyn
Khanisyah Erza Gumilar
Renuka Shanmugalingam
Gustaaf Dekker

doi 10.3389/fcell.2025.1520218

3,696 views

ORIGINAL RESEARCH

Published on 04 Feb 2025

Identification of genes involved in energy metabolism in preeclampsia and discovery of early biomarkers

Ruohua Li
Cuixia Zhou
Kejun Ye
Haihui Chen
Mengjia Peng

doi 10.3389/fimmu.2025.1496046

1,741 views
1 citation

ORIGINAL RESEARCH

Published on 23 Jan 2025

Identification and preliminary validation of biomarkers associated with mitochondrial and programmed cell death in pre-eclampsia

Rong Lin
XiaoYing Weng
Liang Lin
XuYang Hu
ZhiYan Liu
Jing Zheng
FenFang Shen
Rui Li

doi 10.3389/fimmu.2024.1453633

1,486 views
2 citations

ORIGINAL RESEARCH

Published on 04 Sep 2024

First-trimester predictive models for adverse pregnancy outcomes—a base for implementation of strategies to prevent cardiovascular disease development

Ilona Hromadnikova
Katerina Kotlabova
Ladislav Krofta

doi 10.3389/fcell.2024.1461547

1,593 views
1 citation

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Molecular and Cellular Pathology

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Articles

Molecular signatures of preeclampsia subtypes determined through integrated weighted gene co-expression network analysis and differential gene expression analysis of placental transcriptomics

Multiple analytical perspectives of mitochondrial genes in the context of preeclampsia: potential diagnostic markers

Prediction and immune landscape study of potentially key autophagy-related biomarkers in preeclampsia with gestational diabetes mellitus

BNIP3-mediated mitophagy aggravates placental injury in preeclampsia via NLRP1 inflammasome

Evaluating oxidative stress targeting treatments in in vitro models of placental stress relevant to preeclampsia

Secondary prevention of preeclampsia

Identification of genes involved in energy metabolism in preeclampsia and discovery of early biomarkers

Identification and preliminary validation of biomarkers associated with mitochondrial and programmed cell death in pre-eclampsia

First-trimester predictive models for adverse pregnancy outcomes—a base for implementation of strategies to prevent cardiovascular disease development

Frontiers in Cell and Developmental Biology

Molecular and Cellular Pathology