Cell Death in Kidney Diseases: Novel Biomarkers, Mechanisms, and Therapeutic Strategies

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ORIGINAL RESEARCH

Published on 08 Jul 2025

Luteolin delays the progression of IgA nephropathy by attenuating inflammation, oxidative stress and reducing extracellular matrix accumulation through activating the Nrf-2/HO-1 pathway

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ORIGINAL RESEARCH

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ORIGINAL RESEARCH

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doi 10.3389/fphar.2025.1543277

1,642 views

ORIGINAL RESEARCH

Published on 29 Apr 2025

Synergistic amelioration of renal oxidative stress, inflammation, and fibrosis by combination of metformin and Clinacanthus nutans leave extracts in a type 2 diabetic rat model

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doi 10.3389/fphar.2025.1558341

1,154 views

ORIGINAL RESEARCH

Published on 28 Apr 2025

Integrating proteomics and network pharmacology to explore the relevant mechanism of Huangkui capsule in the treatment of chronic glomerulonephritis

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doi 10.3389/fphar.2025.1560420

1,171 views

ORIGINAL RESEARCH

Published on 25 Apr 2025

HDAC3 inhibition mitigates acute kidney injury by alleviating RIPK1-mediated programmed necrosis

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doi 10.3389/fphar.2025.1546950

1,307 views

REVIEW

Published on 24 Apr 2025

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doi 10.3389/fphar.2025.1559026

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ORIGINAL RESEARCH

Published on 16 Apr 2025

Multi - dimensional mechanism analysis of Choerospondias axillaris (Roxb.) Burtt et Hill in treating kidney stones: network pharmacology, molecular docking and in vitro experimental verification

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Xijing Yin
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doi 10.3389/fphar.2025.1501386

1,563 views

REVIEW

Published on 16 Apr 2025

Emerging roles of exosomes in the diagnosis and treatment of kidney diseases

Huanhuan Cao
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Jiajia Ye
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doi 10.3389/fphar.2025.1525314

1,677 views

ORIGINAL RESEARCH

Published on 14 Apr 2025

5-methoxytryptophan ameliorates renal ischemia/reperfusion injury by alleviating endoplasmic reticulum stress-mediated apoptosis through the Nrf2/HO-1 pathway

Shaona Li
Hongjuan Yang
Bing Zhang
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doi 10.3389/fphar.2025.1506482

1,046 views

ORIGINAL RESEARCH

Published on 04 Apr 2025

Endoplasmic reticulum stress aggravates ferroptosis via PERK/ATF4/HSPA5 pathway in UUO-induced renal fibrosis

Zhigang Huang
Lihua Zhou
Bin Liu
Xiaoju Li
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doi 10.3389/fphar.2025.1545972

1,972 views

ORIGINAL RESEARCH

Published on 24 Mar 2025

Yiqi Qingre Gao alleviates renal fibrosis in UUO mice via PI3K/AKT pathway

Qi Jin
Qian Li
Liping Yang
Fang Ma
Huimin Mao
Yuyang Wang
Tongtong Liu
Liang Peng
Ping Li
Yongli Zhan

doi 10.3389/fphar.2025.1538061

1,204 views

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Renal Pharmacology

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Articles

Luteolin delays the progression of IgA nephropathy by attenuating inflammation, oxidative stress and reducing extracellular matrix accumulation through activating the Nrf-2/HO-1 pathway

Homotherapy for heteropathy of chronic kidney disease and oligoasthenozoospermia through regulating SIRT1/NF-κB pathway by Shenqi pills

SuoquanYishen formula improves renal cellular senescence by inhibiting YTHDF1-Rubicon axis to promote autophagy in diabetic kidney disease

Synergistic amelioration of renal oxidative stress, inflammation, and fibrosis by combination of metformin and Clinacanthus nutans leave extracts in a type 2 diabetic rat model

Integrating proteomics and network pharmacology to explore the relevant mechanism of Huangkui capsule in the treatment of chronic glomerulonephritis

HDAC3 inhibition mitigates acute kidney injury by alleviating RIPK1-mediated programmed necrosis

An update on renal tubular injury as related to glycolipid metabolism in diabetic kidney disease

Multi - dimensional mechanism analysis of Choerospondias axillaris (Roxb.) Burtt et Hill in treating kidney stones: network pharmacology, molecular docking and in vitro experimental verification

Emerging roles of exosomes in the diagnosis and treatment of kidney diseases

5-methoxytryptophan ameliorates renal ischemia/reperfusion injury by alleviating endoplasmic reticulum stress-mediated apoptosis through the Nrf2/HO-1 pathway

Endoplasmic reticulum stress aggravates ferroptosis via PERK/ATF4/HSPA5 pathway in UUO-induced renal fibrosis

Yiqi Qingre Gao alleviates renal fibrosis in UUO mice via PI3K/AKT pathway

Frontiers in Pharmacology

Renal Pharmacology