Infection, Immunity and Microecology in Children

The microbiota is increasingly being appreciated as an important mediator in the susceptibility to develop acute and/or chronic respiratory infections and systemic diseases due to the translocation of commensals or pathogens via the circulation or digestive systems. The interactions between the oropharyngeal/ nasopharyngeal microbiota and host mucosal immunity could offer first line protection against potential pathogens. Conversely, these dynamic communities could stimulate inflammatory factors, which might further induce oral and gut dysbiosis linked to many other illnesses.

The goal of this Research Topic is to provide a forum for researchers or/and practitioners to share their observations or insights about aspects of microecology in children. The RT also aims to encourage the coordination of individuals from different research fields to generate a foundation for clinical practice improvement.

We invite contributions addressing the following themes:
● Respiratory infections and microecology in children
● Research focusing on the role of probiotics in the treatment of allergic diseases in children
● Basic and clinical studies on the effects of probiotics on respiratory pathogens in children
● The prevention and treatment of recurrent respiratory tract infections and microflora interventions in children
● The intersection between infectious complications and microbial interventions in the setting of treatment of cancer in children

Keywords: respiratory infections, oropharyngeal/Nasopharyngeal microbiota, oral and gut dysbiosis, flora intervention

Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.