Decoding the Epigenetic Landscape: Elucidating Cancer Pathology and Identifying Novel Therapeutic Targets

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ORIGINAL RESEARCH

Accepted on 13 Jun 2025

Revealing Key Regulatory Factors in Lung adenocarcinoma: The Role of Epigenetic regulation of autophagy-related genes from Transcriptomics, scRNA-seq, and Machine Learning

Zeng Xianchang

doi 10.3389/fphar.2025.1542338

243 views

ORIGINAL RESEARCH

Published on 11 Apr 2025

Integrating multi-omics and experimental techniques to decode ubiquitinated protein modifications in hepatocellular carcinoma

Haikun Yang
Yuan Chen
Zheng Zhou
Yanjing Wang
Peng Li
Yang Li

doi 10.3389/fphar.2025.1545472

1,273 views

ORIGINAL RESEARCH

Published on 19 Mar 2025

The real-world analysis of adverse events with azacitidine: a pharmacovigilance study based on the FAERS and WHO-VigiAccess databases

Zhaorui Wang
Linlin Guo
Youfu He
Baiquan Zhang
Yang Wang
Juan Ding

doi 10.3389/fphar.2025.1555838

2,035 views

ORIGINAL RESEARCH

Published on 18 Mar 2025

Characteristic analysis of adverse reactions of histone deacetylase inhibitors based on WHO-VigiAccess

Tongnan Yin
Yuyu Liu
Chenwen Li
Xinran Feng
Yumeng Lin
Zhongyu Qu

doi 10.3389/fphar.2025.1563797

784 views

ORIGINAL RESEARCH

Published on 19 Feb 2025

Integration of multi-omics profiling reveals an epigenetic-based molecular classification of lung adenocarcinoma: implications for drug sensitivity and immunotherapy response prediction

Ning Wang
Yinan Li
Yaoyao Wang
Wenting Wang

doi 10.3389/fphar.2025.1540477

967 views

ORIGINAL RESEARCH

Published on 18 Feb 2025

Exploring the role of epigenetic regulation in cancer prognosis with epigenetic score

Ruiguang Zhang
Shimin Jin
Qi Xu
Rongxiao Dai

doi 10.3389/fphar.2025.1538205

830 views

ORIGINAL RESEARCH

Published on 14 Feb 2025

Identification of potential diagnostic targets and therapeutic strategies for anoikis-related biomarkers in lung squamous cell carcinoma using machine learning and computational virtual screening

Xin Zhang
Jing Zou
Jinghua Ning
Yanhong Zhao
Run Qu
Yuzhe Zhang

doi 10.3389/fphar.2025.1500968

1,083 views

ORIGINAL RESEARCH

Published on 29 Jan 2025

NCAPD3-mediated ferroptosis of 2,3,5,4’-Tetrahydroxystilbene-2-O-β-D-glucoside inhibits proliferation in T47D cells

Jianfen Shen
Shuo Zhang
Yan Song
Leiming Yang
Qi Huang
Pengyu Wang
Youzhi Zhang

doi 10.3389/fphar.2024.1531220

996 views
1 citation

ORIGINAL RESEARCH

Published on 22 Jan 2025

Development and pan-cancer validation of an epigenetics-based random survival forest model for prognosis prediction and drug response in OS

Chaoyi Yin
Kede Chi
Zhiqing Chen
Shabin Zhuang
Yongsheng Ye
Binshan Zhang
Cailiang Cai

doi 10.3389/fphar.2025.1529525

968 views

ORIGINAL RESEARCH

Published on 15 Jan 2025

Intratumor microbiome-derived butyrate promotes chemo-resistance in colorectal cancer

Linsheng Xu
Bingde Hu
Jingli He
Xin Fu
Na Liu

doi 10.3389/fphar.2024.1510851

1,578 views
2 citations

ORIGINAL RESEARCH

Published on 14 Jan 2025

DNA methylation inhibitors adverse reaction characteristic analysis: an analysis based on the European spontaneous adverse event reporting system

Xia Zhang
Yuyu Liu
Qingwang Hou
Yongxin Guo
Youfu He

doi 10.3389/fphar.2024.1527903

753 views

ORIGINAL RESEARCH

Published on 13 Jan 2025

Integration of histone modification-based risk signature with drug sensitivity analysis reveals novel therapeutic strategies for lower-grade glioma

Jingyuan Wang
Shuai Yan

doi 10.3389/fphar.2024.1523779

1,168 views

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Frontiers in Pharmacology

Pharmacology of Anti-Cancer Drugs

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Frontiers in Oncology
- Pharmacology of Anti-Cancer Drugs
- 3.3 impact factor
- 6.9 citescore

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Articles

Revealing Key Regulatory Factors in Lung adenocarcinoma: The Role of Epigenetic regulation of autophagy-related genes from Transcriptomics, scRNA-seq, and Machine Learning

Integrating multi-omics and experimental techniques to decode ubiquitinated protein modifications in hepatocellular carcinoma

The real-world analysis of adverse events with azacitidine: a pharmacovigilance study based on the FAERS and WHO-VigiAccess databases

Characteristic analysis of adverse reactions of histone deacetylase inhibitors based on WHO-VigiAccess

Integration of multi-omics profiling reveals an epigenetic-based molecular classification of lung adenocarcinoma: implications for drug sensitivity and immunotherapy response prediction

Exploring the role of epigenetic regulation in cancer prognosis with epigenetic score

Identification of potential diagnostic targets and therapeutic strategies for anoikis-related biomarkers in lung squamous cell carcinoma using machine learning and computational virtual screening

NCAPD3-mediated ferroptosis of 2,3,5,4’-Tetrahydroxystilbene-2-O-β-D-glucoside inhibits proliferation in T47D cells

Development and pan-cancer validation of an epigenetics-based random survival forest model for prognosis prediction and drug response in OS

Intratumor microbiome-derived butyrate promotes chemo-resistance in colorectal cancer

DNA methylation inhibitors adverse reaction characteristic analysis: an analysis based on the European spontaneous adverse event reporting system

Integration of histone modification-based risk signature with drug sensitivity analysis reveals novel therapeutic strategies for lower-grade glioma

Frontiers in Pharmacology

Pharmacology of Anti-Cancer Drugs

Participating Journals

Frontiers in Oncology

Pharmacology of Anti-Cancer Drugs