Exploring Antiviral Immune Responses and Therapeutic Strategies Against Human Coronaviruses

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ORIGINAL RESEARCH

Accepted on 14 Aug 2025

Mechanisms Underlying the Mitigating Action of Maxing Shigan Decoction in Acute Lung Injury Caused by Influenza Virus Based on UPLC-HRMS Analysis and Network Pharmacology

Jue Hu
Xiangming Ma
Yufeng Xiao
Chunjing Chen
Chang Liu
Jun Lu
Xiaoqi Wang
Fangguo Lu

doi 10.3389/fimmu.2025.1634442

308 views

ORIGINAL RESEARCH

Published on 04 Jun 2025

Novel NUDCD1 gene variant predisposes to severe COVID-19 disease in Asians through modulation of antiviral DHX15- and MAVS-mediated signalling

Aseervatham Anusha Amali
Douglas Jie Wen Tay
Yiqi Seow
Marie Loh
Sharada Ravikumar
Jocelyn Jin Yu
Shaun Seh Ern Loong
Siew Wai Fong
Chang Jie Mick Lee
19 more
Louis Yi Ann Chai

doi 10.3389/fimmu.2025.1581293

1,484 views

ORIGINAL RESEARCH

Published on 28 Mar 2025

Anti-S2 antibodies responsible for the SARS-CoV-2 infection-induced serological cross-reactivity against MERS-CoV and MERS-related coronaviruses

Siyuan Sun
Jiaying He
Luotian Liu
Yuzhen Zhu
Qingsong Zhang
Yinong Qiu
Yuru Han
Song Xue
Xiaofang Peng
10 more
Qiao Wang

doi 10.3389/fimmu.2025.1541269

1,937 views

ORIGINAL RESEARCH

Published on 28 Mar 2025

Effectiveness of early intervention and combination treatment with monoclonal antibodies and antivirals in oncohematological patients with SARS-CoV-2: a retrospective experience

Silvia Di Bari
Francesco Izzo
Livia Bresciani
Giulia Mancarella
Silvia Garattini
Andrea Gasperin
Daniela Di Trento
Alessandra Grimaldi
Alberico Parente
10 more
Miriam Lichtner

doi 10.3389/fimmu.2025.1524525

1,534 views

BRIEF RESEARCH REPORT

Published on 17 Mar 2025

Non-neutralizing anti-type I interferon autoantibodies could increase thrombotic risk in critical COVID-19 patients

Mario Framil
Lydia García-Serrano
Francisco Morandeira
Juan Francisco Luchoro
Arnau Antolí
Jose Luis Gomez-Vazquez
Àngels Sierra-Fortuny
Xavier Solanich

doi 10.3389/fimmu.2025.1556731

1,068 views

ORIGINAL RESEARCH

Published on 06 Jan 2025

Extracellular acyl-CoA-binding protein as an independent biomarker of COVID-19 disease severity

Stephane Isnard
Tsoarello Mabanga
Léna Royston
Carolina A. Berini
Simeng Bu
Orthy Aiyana
Hansen Feng
Bertrand Lebouché
Cecilia T. Costiniuk
4 more
the Biobanque Québécoise de la COVID-19 (BQC-19)

doi 10.3389/fimmu.2024.1505752

2,067 views
1 citation

ORIGINAL RESEARCH

Published on 27 Nov 2024

Single spike mutation differentiating XBB.1 and XBB.1.5 enhances SARS-CoV-2 cell-to-cell transmission and facilitates serum-mediated enhancement

Elena Criscuolo
Benedetta Giuliani
Matteo Castelli
Mattia Cavallaro
Sofia Sisti
Roberto Burioni
Davide Ferrari
Nicasio Mancini
Massimo Locatelli
Nicola Clementi

doi 10.3389/fimmu.2024.1501200

1,457 views
1 citation

ORIGINAL RESEARCH

Published on 27 Nov 2024

Prognostic performance of early immune and endothelial activation markers in mild-to-moderate COVID-19 outpatients: a nested case-control study

Andrea Alemany
Núria Balanza
Pere Millat-Martinez
Dan Ouchi
Marc Corbacho-Monné
Cristian Morales-Indiano
Gema Fernández Rivas
Ignacio Blanco
Oriol Mitjà
5 more
COnV-ert BMK STUDY GROUP

doi 10.3389/fimmu.2024.1501872

4,808 views
1 citation

REVIEW

Published on 26 Nov 2024

Exosomes and SARS-CoV-2 infection

Liuying Li
Zixuan Yang
Jia Li

doi 10.3389/fimmu.2024.1467109

2,663 views
3 citations

ORIGINAL RESEARCH

Published on 24 Oct 2024

IgG1 versus IgG3: influence of antibody-specificity and allotypic variance on virus neutralization efficacy

Somanath Kallolimath
Lin Sun
Roman Palt
Esther Föderl-Höbenreich
Antonia Hermle
Leonie Voss
Marina Kleim
Falk Nimmerjahn
Johannes S. Gach
5 more
Herta Steinkellner

doi 10.3389/fimmu.2024.1490515

1,879 views
1 citation

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Viral Immunology

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Articles

Mechanisms Underlying the Mitigating Action of Maxing Shigan Decoction in Acute Lung Injury Caused by Influenza Virus Based on UPLC-HRMS Analysis and Network Pharmacology

Novel NUDCD1 gene variant predisposes to severe COVID-19 disease in Asians through modulation of antiviral DHX15- and MAVS-mediated signalling

Anti-S2 antibodies responsible for the SARS-CoV-2 infection-induced serological cross-reactivity against MERS-CoV and MERS-related coronaviruses

Effectiveness of early intervention and combination treatment with monoclonal antibodies and antivirals in oncohematological patients with SARS-CoV-2: a retrospective experience

Non-neutralizing anti-type I interferon autoantibodies could increase thrombotic risk in critical COVID-19 patients

Extracellular acyl-CoA-binding protein as an independent biomarker of COVID-19 disease severity

Single spike mutation differentiating XBB.1 and XBB.1.5 enhances SARS-CoV-2 cell-to-cell transmission and facilitates serum-mediated enhancement

Prognostic performance of early immune and endothelial activation markers in mild-to-moderate COVID-19 outpatients: a nested case-control study

Exosomes and SARS-CoV-2 infection

IgG1 versus IgG3: influence of antibody-specificity and allotypic variance on virus neutralization efficacy

Frontiers in Immunology

Viral Immunology