Nanostructured materials have emerged as a cornerstone in the field of targeted drug delivery, offering remarkable potential to enhance the precision, efficacy, and safety of therapeutic interventions. These materials, defined by their nanoscale architecture, exhibit unique properties such as a high surface area-to-volume ratio, tunable chemical functionalities, and the ability to interact specifically with biological molecules. Such attributes make them ideal candidates for designing drug delivery systems that can overcome the limitations of traditional therapies.
One of the most significant advantages of nanostructured materials in targeted drug delivery is their ability to be engineered for specific interactions with diseased cells or tissues. By functionalizing the surface of nanoparticles, liposomes, or dendrimers with targeting ligands (such as antibodies, peptides, or small molecules) can direct these carriers to selectively bind to receptors overexpressed on target cells, such as cancer cells. This targeted approach ensures that therapeutic agents are delivered precisely where they are needed, thereby maximizing their therapeutic effect while minimizing off-target side effects.
Additionally, the versatility of nanostructured materials allows for the incorporation of controlled release mechanisms. These materials can be designed to release their payload in response to specific stimuli, such as pH changes, temperature shifts, or external triggers like light or magnetic fields. This controlled release capability ensures that drugs are delivered at the right time and place, further enhancing therapeutic outcomes.
Overall, nanostructured materials represent a powerful tool in the advancement of targeted drug delivery, promising to revolutionize treatment strategies for a wide range of diseases. Therefore, this research topic seeks to present a comprehensive, up-to-date collection of studies focusing on nanostructured material in target drug delivery. We invite contributions in the form of Original Research Articles, Reviews, Mini-Reviews, Systematic Reviews, Perspectives, Commentaries, Data Notes, and Technical Notes. Topics of interest include, but are not limited to:
• Research focusing on nanostructured materials that enhances drug loading capacity and facilitates efficient drug delivery.
• Studies related to encapsulation of therapeutic agents that enhances the stability and bioavailability of the drugs.
• Surface modification of nanostructured materials with targeting ligands (e.g., antibodies, peptides) allows for specific interaction with diseased cells, improving the precision of drug delivery.
• Research that focusses on enhancing the drug loading capacity of nanostructured materials, exploring different types of nanostructures (e.g., nanoparticles, nanogels) and surface modifications.
• Focusing on disease-specific nanostructured drug delivery systems, such as those tailored for cancer, neurodegenerative diseases, or infectious diseases, to enhance treatment outcomes.
Keywords:
Nanostructured Materials, Nanogel, Nanoparticles, Targeted Drug Delivery
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
Nanostructured materials have emerged as a cornerstone in the field of targeted drug delivery, offering remarkable potential to enhance the precision, efficacy, and safety of therapeutic interventions. These materials, defined by their nanoscale architecture, exhibit unique properties such as a high surface area-to-volume ratio, tunable chemical functionalities, and the ability to interact specifically with biological molecules. Such attributes make them ideal candidates for designing drug delivery systems that can overcome the limitations of traditional therapies.
One of the most significant advantages of nanostructured materials in targeted drug delivery is their ability to be engineered for specific interactions with diseased cells or tissues. By functionalizing the surface of nanoparticles, liposomes, or dendrimers with targeting ligands (such as antibodies, peptides, or small molecules) can direct these carriers to selectively bind to receptors overexpressed on target cells, such as cancer cells. This targeted approach ensures that therapeutic agents are delivered precisely where they are needed, thereby maximizing their therapeutic effect while minimizing off-target side effects.
Additionally, the versatility of nanostructured materials allows for the incorporation of controlled release mechanisms. These materials can be designed to release their payload in response to specific stimuli, such as pH changes, temperature shifts, or external triggers like light or magnetic fields. This controlled release capability ensures that drugs are delivered at the right time and place, further enhancing therapeutic outcomes.
Overall, nanostructured materials represent a powerful tool in the advancement of targeted drug delivery, promising to revolutionize treatment strategies for a wide range of diseases. Therefore, this research topic seeks to present a comprehensive, up-to-date collection of studies focusing on nanostructured material in target drug delivery. We invite contributions in the form of Original Research Articles, Reviews, Mini-Reviews, Systematic Reviews, Perspectives, Commentaries, Data Notes, and Technical Notes. Topics of interest include, but are not limited to:
• Research focusing on nanostructured materials that enhances drug loading capacity and facilitates efficient drug delivery.
• Studies related to encapsulation of therapeutic agents that enhances the stability and bioavailability of the drugs.
• Surface modification of nanostructured materials with targeting ligands (e.g., antibodies, peptides) allows for specific interaction with diseased cells, improving the precision of drug delivery.
• Research that focusses on enhancing the drug loading capacity of nanostructured materials, exploring different types of nanostructures (e.g., nanoparticles, nanogels) and surface modifications.
• Focusing on disease-specific nanostructured drug delivery systems, such as those tailored for cancer, neurodegenerative diseases, or infectious diseases, to enhance treatment outcomes.
Keywords:
Nanostructured Materials, Nanogel, Nanoparticles, Targeted Drug Delivery
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.