The Application of Immune Checkpoint Inhibitors Combined with Chemotherapy in Tumor Immunotherapy

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ORIGINAL RESEARCH

Published on 13 Aug 2025

Efficacy and safety of first-line chemotherapy combined with immune checkpoint inhibitors for extensive-stage small cell lung cancer patients: a real-world propensity score matching study

Bin Jia
Chenyi Zhou
Fei Zhao
Xiaoru Song
Yuan Ding
Xiyin Wang
Boying Wu
Huina Wang
Quanman Hu
Shuaiyin Chen

doi 10.3389/fimmu.2025.1562458

433 views

ORIGINAL RESEARCH

Published on 18 Jul 2025

Development and validation of nomogram for predicting pathological complete response to neoadjuvant chemotherapy and immunotherapy for locally advanced gastric cancer: a multicenter real-world study in China

Hao Cui
Rui Li
Liqiang Song
Yongpu Yang
Zhen Yuan
Xin Zhou
Junfeng Du
Chaojun Zhang
Hong Xu
3 more
Bo Wei

doi 10.3389/fimmu.2025.1603196

1,071 views

CASE REPORT

Published on 30 Jun 2025

Cadonilimab combined with trastuzumab and chemotherapy for HER2-positive gastric cancer with bone marrow metastasis and DIC: a case report and literature review

Meijing Chen
Jiwen Fan
Danyang Zhou
Boran Cheng
Shubin Wang
Gangling Tong

doi 10.3389/fimmu.2025.1608636

2,149 views
1 citation

CASE REPORT

Published on 30 Jun 2025

Long-term survival in advanced pulmonary large-cell neuroendocrine carcinoma after multi-line immunochemotherapy and anti-angiogenic therapy: a case report

Hongming Wang
Shiyan Li
Xiaoyang Liu
Yan Zhang
Jiang Zheng
Yangfeng Du
Zemin Xiao
Nuoni Wang
Zhijun Wu

doi 10.3389/fimmu.2025.1618672

1,443 views

CASE REPORT

Published on 26 Jun 2025

Durable immunotherapeutic response in molecularly complex pulmonary adenosquamous carcinoma: case report and literature review

Jun Zhu
Xin Xun
Jiayun Liu
Bin Su
Yi Li
Hong Chen
Meijin Huang

doi 10.3389/fimmu.2025.1614283

1,442 views

ORIGINAL RESEARCH

Published on 20 Jun 2025

Total neoadjuvant immunochemotherapy for proficient mismatch repair or microsatellite stable locally advanced rectal cancer

Xing Li
Ligong Tang
Fangyuan Cheng
Yongchao Xu

doi 10.3389/fimmu.2025.1611386

1,188 views

ORIGINAL RESEARCH

Published on 20 May 2025

B and T lymphocyte attenuator (BTLA) and PD-1 pathway dual blockade promotes antitumor immune responses by reversing CD8+ T-cell exhaustion in non-small cell lung cancer

Yang Zhang
Yang Yang
Yuanyuan Zeng
Qiuxia Qu
Dan Shen
Chuanyong Mu
Wei Lei
Meiqin Su
Jingyu Mao
3 more
Jian-an Huang

doi 10.3389/fimmu.2025.1553042

2,077 views

CASE REPORT

Published on 01 May 2025

Complete remission of a high-risk, locally advanced cervical cancer with para-aortic lymph node metastases treated with first-line tislelizumab plus bevacizumab combined with chemotherapy followed by radiotherapy with maintenance therapy: a case report

Juan Lang
Qianqian Liu
Rong Ji
Miao Qiu
Siben Wang
Qingmeng Liu
Dapeng Li
Ping Chen
Zhongkui Xiong

doi 10.3389/fimmu.2025.1573202

1,839 views

ORIGINAL RESEARCH

Published on 28 Apr 2025

The administration sequences of immune checkpoint inhibitors and chemotherapy cause discrete efficacy when treating non-small cell lung cancer: a retrospective study

Bicheng Zhang
Yuxiao Song
Qian Min
Weiting Cheng
Jun Wang
Yang Fu
Jiaxin Yin

doi 10.3389/fimmu.2025.1579420

1,243 views

ORIGINAL RESEARCH

Published on 14 Apr 2025

Comparison of immunotherapy based total neoadjuvant therapy or standard neoadjuvant chemoradiation for locally advanced rectal cancer: a multi-institutional retrospective study

Wen Zhao
Wenxing Gao
Jitao Du
Dingchang Li
Xianqiang Liu
Zhengyao Chang
Peng Chen
Xu Sun
Yingjie Zhao
2 more
Guanglong Dong

doi 10.3389/fimmu.2025.1513716

1,353 views

REVIEW

Published on 08 Apr 2025

Efficacy and safety of programmed cell death protein-1 inhibitor for first-line therapy of advanced gastric or gastroesophageal junction cancer: a network meta-analysis

Yunnan Zhang
Wenxing Peng
Wei Yang
Wenzhou Zhang
Yannan Fan

doi 10.3389/fimmu.2025.1500954

2,100 views

ORIGINAL RESEARCH

Published on 27 Mar 2025

Neoadjuvant immunotherapy for NSCLC: superior combination strategies, optimal treatment cycles, and predictive indicators from a Bayesian meta-analysis

Yubingxue Liu
Jianlin Long
Huan Deng
Wen Chen

doi 10.3389/fimmu.2025.1548665

2,601 views

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Cancer Immunity and Immunotherapy

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Frontiers in Oncology
- Cancer Immunity and Immunotherapy
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Articles

Efficacy and safety of first-line chemotherapy combined with immune checkpoint inhibitors for extensive-stage small cell lung cancer patients: a real-world propensity score matching study

Development and validation of nomogram for predicting pathological complete response to neoadjuvant chemotherapy and immunotherapy for locally advanced gastric cancer: a multicenter real-world study in China

Cadonilimab combined with trastuzumab and chemotherapy for HER2-positive gastric cancer with bone marrow metastasis and DIC: a case report and literature review

Long-term survival in advanced pulmonary large-cell neuroendocrine carcinoma after multi-line immunochemotherapy and anti-angiogenic therapy: a case report

Durable immunotherapeutic response in molecularly complex pulmonary adenosquamous carcinoma: case report and literature review

Total neoadjuvant immunochemotherapy for proficient mismatch repair or microsatellite stable locally advanced rectal cancer

B and T lymphocyte attenuator (BTLA) and PD-1 pathway dual blockade promotes antitumor immune responses by reversing CD8+ T-cell exhaustion in non-small cell lung cancer

Complete remission of a high-risk, locally advanced cervical cancer with para-aortic lymph node metastases treated with first-line tislelizumab plus bevacizumab combined with chemotherapy followed by radiotherapy with maintenance therapy: a case report

The administration sequences of immune checkpoint inhibitors and chemotherapy cause discrete efficacy when treating non-small cell lung cancer: a retrospective study

Comparison of immunotherapy based total neoadjuvant therapy or standard neoadjuvant chemoradiation for locally advanced rectal cancer: a multi-institutional retrospective study

Efficacy and safety of programmed cell death protein-1 inhibitor for first-line therapy of advanced gastric or gastroesophageal junction cancer: a network meta-analysis

Neoadjuvant immunotherapy for NSCLC: superior combination strategies, optimal treatment cycles, and predictive indicators from a Bayesian meta-analysis

Frontiers in Immunology

Cancer Immunity and Immunotherapy

Participating Journals

Frontiers in Oncology

Cancer Immunity and Immunotherapy