Neurobiological mechanisms and psychological processes involved in the origin and development of trauma and depression

Trauma and depression are deeply intertwined phenomena with significant impacts on mental health. Understanding their origins and progression hinges on exploring both neurobiological mechanisms and psychological processes. Recent advances in neuroscience have shed light on how neural circuits, neurotransmitter systems, and genetic factors contribute to these conditions. Concurrently, psychological research illuminates how cognitive, emotional, and social dynamics influence the onset and evolution of trauma and depression. This dual approach enhances our ability to unravel these complex disorders and develop effective interventions.

The primary goal of this Research Topic is to deepen our understanding of the interplay between biological and psychological factors in trauma and depression. By addressing key questions about their origins and developmental trajectories, we aim to pave the way for innovative therapeutic strategies. This collection seeks to foster interdisciplinary dialogue, encouraging collaboration between neuroscientists, psychologists, and clinicians. Our objective is to compile research that not only deciphers the mechanisms of these conditions but also proposes practical solutions for prevention and treatment.

We invite contributions that explore a range of specific themes including, but not limited to:

- Neurobiological underpinnings of trauma and depression, such as brain circuit disruptions, neuroinflammation, and epigenetic modifications.

- Psychological processes implicated in the onset and maintenance of these disorders, including cognitive biases, emotional regulation, and interpersonal factors.

- Interaction between genetic predispositions and environmental stressors in the development of trauma and depression.

- Innovative methodologies for studying neurobiological and psychological aspects, leveraging technologies like neuroimaging and computational modeling.

- Translational research that links basic scientific findings to clinical applications, focusing on novel therapeutic approaches.

- Case studies or reviews that synthesize current knowledge and identify future research directions.

Authors are encouraged to submit original research articles, review articles, and theoretical papers that align with these themes, promoting a cohesive understanding of trauma and depression.