Model-Informed Approaches: Uniting Drug Development with Personalized Medicine

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ORIGINAL RESEARCH

Accepted on 10 Nov 2025

Combining Mechanistic Quantitative Systems Pharmacology Modeling and Patient-Derived Organoid Testing in MET-aberrant Non-Small Cell Lung Cancer for High-throughput Combination Efficacy Analysis and Personalized Treatment Design

Jingjing Hu
Qi Rao
Yanyong Zhao
Geli Li
Zichen Jiao
Haoxiang Wang
Yu-Chen Qu
Shihui Xu
Zhongze Gu
3 more
Guohua Zhou

ORIGINAL RESEARCH

Published on 18 Aug 2025

Published population pharmacokinetic models of mycophenolate sodium: a systematic review and external evaluation in a Chinese sample of renal transplant recipients

Tong Gao
Wen Xu
Xiao Li
Qie Guo
Donghua Liu
Xiaolei Zhang
Ping Leng
Jialin Sun

doi 10.3389/fphar.2025.1632568

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Frontiers in Pharmacology

Frontiers in Pharmacology

Experimental Pharmacology and Drug Discovery

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