Parasite-Induced Liver Diseases Volume II

Parasitic diseases are still the primary diseases that seriously threaten human health and life, and liver pathology is the leading cause of morbidity and mortality for various parasitic diseases, such as schistosomiasis, clonorchiasis, and hydatidosis. Most of parasite-induced liver pathologies, including liver injury, inflammation, fibrosis, and even cancer, are still lack of effective therapy. The interactions between parasites and host hepatic resident cells or recruited inflammatory cells are fundamental to the occurrence of these pathologies. A better understanding of the mechanisms underpinning these pathologies is the key to developing novel therapeutic interventions for these debilitating diseases.

This Research Topic aims to provide a unique perspective for understanding the cellular and molecular mechanisms of liver pathologies induced by parasite infections and developing new biomarker-based diagnostics and treatment modalities for these debilitating hepatic diseases.

We welcome high-quality contributions, including Original Research and Review, addressing the following scope areas:
• Key parasite-derived pathogenetic molecules responsible for the initiation of liver pathologies
• Key host cellular and molecular mechanisms regulating the initiation, progression and regression of parasite-induced liver pathologies
• Novel biomarkers for parasite-induced liver pathologies
• Novel therapeutic interventions for parasite-induced liver pathologies
• Omics research in parasitic liver diseases
• Novel techniques for studying parasitic liver diseases
• Animal or cell models for studying parasitic liver diseases